Julian S. Northen

Newcastle University — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index475citations35works0.02yr avg
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Research Topics

Chemical Synthesis and Analysis(12), HIV/AIDS drug development and treatment(10), Asymmetric Synthesis and Catalysis(9), Biochemical and Molecular Research(9), Synthesis and Characterization of Heterocyclic Compounds(8)

Publications35 total

Data from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S1 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S2 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S2 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S3 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S1 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Data from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Supplementary Fig. S3 from Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
2023Open Access
Process Development toward a Pro-Drug of Buprenorphine
Organic Process Research & Development·2019· 1 cited
Sterol 3β-glucosyltransferase biocatalysts with a range of selectivities, including selectivity for testosterone
Molecular BioSystems·2013· 4 citedOpen Access
Nucleoside Transport Inhibitors: Structure−Activity Relationships for Pyrimido[5,4-<i>d</i>]pyrimidine Derivatives That Potentiate Pemetrexed Cytotoxicity in the Presence of α<sub>1</sub>-Acid Glycoprotein
Journal of Medicinal Chemistry·2011· 16 cited
Synthesis of sulfonamide-based kinase inhibitors from sulfonates by exploiting the abrogated SN2 reactivity of 2,2,2-trifluoroethoxysulfonates
Organic & Biomolecular Chemistry·2010· 16 cited
Preclinical evaluation of a novel pyrimidopyrimidine for the prevention of nucleoside and nucleobase reversal of antifolate cytotoxicity
Molecular Cancer Therapeutics·2009· 9 citedOpen Access
Parallel kinetic resolution of active esters using designer oxazolidin-2-ones derived from phenylglycine
Tetrahedron Asymmetry·2008· 11 cited
Parallel kinetic resolution of racemic oxazolidinones using quasi-enantiomeric active esters
Tetrahedron Asymmetry·2007· 16 cited
Parallel kinetic resolution of an oxazolidinone using a <i>quasi</i>‐enantiomeric combination of [D,<sup>13</sup>C]‐isotopomers of pentafluorophenyl 2‐phenyl propionate
Chirality·2007· 12 cited
Mutual kinetic separation of isotopomers of pentafluorophenyl 2‐phenyl propionate using quasi‐enantiomeric oxazolidinones
Chirality·2007· 12 cited
Synthesis of enantiomerically pure isotopomers of 2‐phenylpropionic acids
Chirality·2007· 1 cited
Synthesis, characterisation and application of enantiomeric isotopomers of Evans’ oxazolidinones
Tetrahedron Asymmetry·2006· 14 cited
Small-Molecule Inhibitors of the MDM2-p53 Protein−Protein Interaction Based on an Isoindolinone Scaffold
Journal of Medicinal Chemistry·2006· 144 citedOpen Access
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Frequent Co-authors

Bernard T. Golding(15), Roger J. Griffin(15), Nicola J. Curtin(13), Anthony Flinn(13), David R. Newell(12), Kappusamy Saravanan(12), Jason Eames(12), Gregory S. Coumbarides(11), Marco Dingjan(11), Hannah Barlow(10), Marion Barton(10), Huw D. Thomas(10), Lan-Zhen Wang(10), Mei‐Ju Lin(9), Yonas Yohannes(8), Sameer Chavda(5), Ian R. Hardcastle(3), Elliot Coulbeck(3), Kenny Tenza(3), David O’Hagan(3)