Bruno Ségui

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

35h-index3.8kcitations180works0.62yr avg
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Research Topics

Sphingolipid Metabolism and Signaling(67), Cancer Immunotherapy and Biomarkers(31), Immunotherapy and Immune Responses(31), CAR-T cell therapy research(23), Lipid Membrane Structure and Behavior(21)

Publications180 total

TNF blockade with certolizumab improves the efficacy of anti-PD-1 and anti-CTLA-4 combination therapy for melanoma
2026
The Phospholipid Bis(monoacylglycero)Phosphate Confers Antitumour Immunogenicity to Exosomes Secreted by Dendrogenin A, Which Activates Its Biosynthesis in Tumour Cells
Journal of Extracellular Vesicles·2026Open Access
Image-guided intensity-modulated radiotherapy with reduced margins in patients with prostate cancer: Results of the RCMIGI randomized phase II trial
Radiotherapy and Oncology·2025
Kyste prostatique une cause rare de dysurie chez le jeune : à propos d’une observation clinique
Progrès en Urologie - FMC·2025
<scp>TNF</scp> signature in advanced melanoma patients treated with immune checkpoint inhibitors: Results from the <scp>MELANFα</scp> clinical study
International Journal of Cancer·2025· 1 citedOpen Access
Targeting ceramide metabolism in melanoma to improve the efficacy of immune checkpoint inhibitor therapy: from basic mechanisms to the clinic.
SPIRE - Sciences Po Institutional REpository·2024
Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation and predict resistance to immune checkpoint inhibitors in advanced melanoma patients
Frontiers in Immunology·2024· 3 citedOpen Access
A fluorogenic substrate for the detection of lipid amidases in intact cells
Journal of Lipid Research·2024· 1 citedOpen Access
Sphingolipid paracrine signaling impairs keratinocyte adhesion to promote melanoma invasion
Cell Reports·2023· 17 citedOpen Access
Protective Role of RIPK1 Scaffolding against HDV-Induced Hepatocyte cell death and the Significance of Cytokines in Mice
2023Open Access
Ceramide metabolism alterations contribute to Tumor Necrosis Factor-induced melanoma dedifferentiation: from basic research to immunotherapy in advanced melanoma patients.
SPIRE - Sciences Po Institutional REpository·2023
Supplementary Data File S1 from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Data from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Data File S1 from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Tables and Figures from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Data File S2 from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Data File S2 from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Data from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Tables and Figures from Neutral Sphingomyelinase 2 Heightens Anti-Melanoma Immune Responses and Anti–PD-1 Therapy Efficacy
2023Open Access
Supplementary Figure S3 from Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas
2023Open Access
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Frequent Co-authors

Thierry Levade(35), Nathalie Andrieu‐Abadie(26), Céline Colacios(12), Virginie Garcia(12), Anne Montfort(9), Hervé Benoist(9), Stéphane Carpentier(9), Nicolás Meyer(8), Robert Salvayre(8), Thomas Filleron(7), Silvia Arcucci(7), Caroline Imbert(6), Julia Gilhodes(5), Philippe Rochaix(5), Jean‐Pierre Jaffrézou(5), Olivier Cuvillier(5), Carine Dufau(5), Florie Bertrand(4), Sophie Malagarie‐Cazenave(4), Valérie Gouazé‐Andersson(4)