Paolo Santambrogio

Vita-Salute San Raffaele University — Italy

Medicine · Health Sciences

47h-index6.7kcitations115works4.02yr avg
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Research Topics

Iron Metabolism and Disorders(70), Trace Elements in Health(40), Hemoglobinopathies and Related Disorders(28), RNA regulation and disease(21), Neurological diseases and metabolism(21)

Publications114 total

Neuroferritinopathy Human-Induced Pluripotent Stem Cell-Derived Astrocytes Reveal an Active Role of Free Intracellular Iron in Astrocyte Reactivity
International Journal of Molecular Sciences·2025· 2 citedOpen Access
Fibroblasts and <scp>hiPS</scp>‐Derived Astrocytes From <scp>CoPAN</scp> Patients Showed Different Levels of Iron Overload Correlated With Senescent Phenotype
Glia·2025· 2 citedOpen Access
Mitochondrial iron deficiency triggers cytosolic iron overload in PKAN hiPS-derived astrocytes
Cell Death and Disease·2024· 8 citedOpen Access
Data from Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models
2023Open Access
Supplementary Data from Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models
2023Open Access
Data from Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models
2023Open Access
Supplementary Data from Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models
2023Open Access
PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes
Pharmaceutics·2023· 7 citedOpen Access
780 POTENTIAL RELATIONSHIP BETWEEN MITOCHONDRIAL FERRITIN EXPRESSION AND CARDIOTOXICITY IN PATIENTS UNDERGOING ANTHRACYLINE CHEMOTHERAPY
European Heart Journal Supplements·2022· 1 citedOpen Access
PKAN hiPS-Derived Astrocytes Show Impairment of Endosomal Trafficking: A Potential Mechanism Underlying Iron Accumulation
Frontiers in Cellular Neuroscience·2022· 9 citedOpen Access
Massive iron accumulation in PKAN-derived neurons and astrocytes: light on the human pathological phenotype
Cell Death and Disease·2022· 45 citedOpen Access
H-Ferritin Produced by Myeloid Cells Is Released to the Circulation and Plays a Major Role in Liver Iron Distribution during Infection
International Journal of Molecular Sciences·2021· 13 citedOpen Access
Mitochondrial Ferritin: Its Role in Physiological and Pathological Conditions
Cells·2021· 53 citedOpen Access
Pathogenic mechanism and modeling of neuroferritinopathy
Cellular and Molecular Life Sciences·2021· 17 citedOpen Access
Neuronal Ablation of CoA Synthase Causes Motor Deficits, Iron Dyshomeostasis, and Mitochondrial Dysfunctions in a CoPAN Mouse Model
International Journal of Molecular Sciences·2020· 19 citedOpen Access
Iron Induces Cell Death and Strengthens the Efficacy of Antiandrogen Therapy in Prostate Cancer Models
Clinical Cancer Research·2020· 73 citedOpen Access
Harmful Iron-Calcium Relationship in Pantothenate kinase Associated Neurodegeneration
International Journal of Molecular Sciences·2020· 26 citedOpen Access
Stem Cell Modeling of Neuroferritinopathy Reveals Iron as a Determinant of Senescence and Ferroptosis during Neuronal Aging
Stem Cell Reports·2019· 75 citedOpen Access
Iron Pathophysiology in Neurodegeneration with Brain Iron Accumulation
Advances in experimental medicine and biology·2019· 20 cited
Mitochondrial Ferritin Is a Hypoxia-Inducible Factor 1α-Inducible Gene That Protects from Hypoxia-Induced Cell Death in Brain
Antioxidants and Redox Signaling·2018· 56 cited
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Frequent Co-authors

Sonia Levi(34), Paolo Arosio(27), Anna Cozzi(22), Alberto Albertini(8), Barbara Corsi(8), Ermanna Rovida(6), Alessandro Campanella(6), Gaetano Cairo(4), Barbara Garavaglia(4), Vania Broccoli(4), Giorgio Biasiotto(3), Arnulf H. Koeppen(3), Carole Beaumont(3), Béatrice Langlois d’Estaintot(3), T. Granier(3), B. Gallois(3), Fadi Bou‐Abdallah(3), N. Dennis Chasteen(3), Alicia Rubio(3), Stefano Taverna(3)