Sophie C. Cazanave

Medicine · Health Sciences

28h-index4.7kcitations55works2.02yr avg
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Research Topics

Liver Disease Diagnosis and Treatment(35), Endoplasmic Reticulum Stress and Disease(20), Diet, Metabolism, and Disease(9), Liver physiology and pathology(7), Cell death mechanisms and regulation(5)

Publications55 total

Expandable, Functional Hepatocytes Derived from Primary Cells Enable Liver Therapeutics
2024· 2 citedOpen Access
Novel and accurate measurement of differential protease activity in diagnosed HCC patients compared to non-HCC cirrhotic patients
Journal of Hepatology·2022
Measurement of protease activity using novel plasma biosensors can accurately detect hepatocellular carcinoma
Journal of Hepatology·2022
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors
Science Translational Medicine·2021· 24 cited
Identification of a Metabolic, Transcriptomic, and Molecular Signature of Patatin‐Like Phospholipase Domain Containing 3–Mediated Acceleration of Steatohepatitis
Hepatology·2020· 65 citedOpen Access
Glympse liver test for noninvasive monitoring of combination drug therapy in a rat model of non-alcoholic steatohepatitis (NASH)
Journal of Hepatology·2020Open Access
Author Correction: The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
Scientific Reports·2020Open Access
SAT-281-Protease activity sensors for non-invasive monitoring of NASH
Journal of Hepatology·2019· 2 cited
Haptoglobin 2 Allele is Associated With Histologic Response to Vitamin E in Subjects With Nonalcoholic Steatohepatitis
Journal of Clinical Gastroenterology·2018· 23 citedOpen Access
Acceleration of NASH in a mouse model provides novel insights on the mechanisms by which I148M PNPLA3 drives steatohepatitis
Journal of Hepatology·2018
The Transcriptomic Signature Of Disease Development And Progression Of Nonalcoholic Fatty Liver Disease
Scientific Reports·2017· 66 citedOpen Access
The presence and severity of nonalcoholic steatohepatitis is associated with specific changes in circulating bile acids
Hepatology·2017· 401 citedOpen Access
Key molecular signatures of disease development and progression in non-alcoholic fatty liver disease in humans
Journal of Hepatology·2017
A diet-induced animal model of non-alcoholic fatty liver disease and hepatocellular cancer
Journal of Hepatology·2016· 522 citedOpen Access
FTY720/Fingolimod Reduces Steatosis in a Murine Model of Non‐Alcoholic Fatty Liver Disease
The FASEB Journal·2016
Sa1672 Manassatin, a Plant Based Compound Ameliorates AMPK and Suppresses ERK1/2 Pathways in Human Hepatocytes - A Novel Therapeutic Target for Nonalcoholic Fatty Liver Disease
Gastroenterology·2016
Molecular mechanisms of lipotoxicity and glucotoxicity in nonalcoholic fatty liver disease
Metabolism·2016· 557 citedOpen Access
Omega-3 Carboxylic Acids, Epanova®, and the Sodium-Glucose Co-Transporter 2 Inhibitor, Dapagliflozin®, Improve Steatohepatitis and Fibrosis Scoring in a Mouse Model of Non-Alcoholic Steatohepatitis
Journal of Hepatology·2016· 2 cited
Molecular Mechanisms of Lipotoxicity in Nonalcoholic Fatty Liver Disease
2015· 5 cited
Dysregulated Hepatic Methionine Metabolism Drives Homocysteine Elevation in Diet-Induced Nonalcoholic Fatty Liver Disease
PLoS ONE·2015· 134 citedOpen Access
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Frequent Co-authors

Gregory J. Gores(19), Arun J. Sanyal(14), Steven F. Bronk(14), Justin L. Mott(13), Nathan W. Werneburg(11), Bubu A. Banini(8), Faridoddin Mirshahi(8), Pierre Bédossa(8), Amon Asgharpour(7), Mulugeta Seneshaw(6), Kalyani Daita(6), Hae‐Ki Min(6), Yuko Akazawa(6), Nafisa A. Elmi(6), Divya P. Kumar(5), Michael Charlton(5), Prasanna K. Santhekadur(5), Christian D. Fingas(5), Maria Eugenia Guicciardi(5), Abdul M. Oseini(5)