José Luis Nájera

Institut thématique Génétique, génomique et bioinformatique — France

Medicine · Health Sciences

22h-index1.6kcitations33works0.02yr avg
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Research Topics

Herpesvirus Infections and Treatments(16), HIV Research and Treatment(15), Immunotherapy and Immune Responses(14), Poxvirus research and outbreaks(13), vaccines and immunoinformatics approaches(10)

Publications33 total

Genetics of lymphomas in Ecuador
Blood·2025Open Access
NYVAC vector modified by C7L viral gene insertion improves T cell immune responses and effectiveness against leishmaniasis
Virus Research·2016· 5 cited
Suppression of NYVAC Infection in HeLa Cells Requires RNase L but Is Independent of Protein Kinase R Activity
Journal of Virology·2015· 1 citedOpen Access
NFκB activation by modified vaccinia virus as a novel strategy to enhance neutrophil migration and HIV-specific T-cell responses
Proceedings of the National Academy of Sciences·2015· 32 citedOpen Access
Vaccinia Virus with Selective Deletions Enhances T Cell Response to HIV Antigens by Specific Neutrophil Recruitment
AIDS Research and Human Retroviruses·2014
Deletion of the Viral Anti-Apoptotic Gene F1L in the HIV/AIDS Vaccine Candidate MVA-C Enhances Immune Responses against HIV-1 Antigens
PLoS ONE·2012· 34 citedOpen Access
Removal of Vaccinia Virus Genes That Block Interferon Type I and II Pathways Improves Adaptive and Memory Responses of the HIV/AIDS Vaccine Candidate NYVAC-C in Mice
Journal of Virology·2012· 41 citedOpen Access
Safety and immunogenicity of a modified pox vector-based HIV/AIDS vaccine candidate expressing Env, Gag, Pol and Nef proteins of HIV-1 subtype B (MVA-B) in healthy HIV-1-uninfected volunteers: A phase I clinical trial (RISVAC02)
Vaccine·2011· 80 citedOpen Access
A Candidate HIV/AIDS Vaccine (MVA-B) Lacking Vaccinia Virus Gene C6L Enhances Memory HIV-1-Specific T-Cell Responses
PLoS ONE·2011· 75 citedOpen Access
The HIV/AIDS Vaccine Candidate MVA-B Administered as a Single Immunogen in Humans Triggers Robust, Polyfunctional, and Selective Effector Memory T Cell Responses to HIV-1 Antigens
Journal of Virology·2011· 75 citedOpen Access
MVA and NYVAC as Vaccines against Emergent Infectious Diseases and Cancer
Current Gene Therapy·2011· 109 cited
T-Cell Immune Responses Against Env from CRF12_BF and Subtype B HIV-1 Show High Clade-Specificity that Can Be Overridden by Multiclade Immunizations
PLoS ONE·2011· 3 citedOpen Access
Diversity in Viral Anti-PKR Mechanisms: A Remarkable Case of Evolutionary Convergence
PLoS ONE·2011· 21 citedOpen Access
The HIV/AIDS vaccine candidate MVA-B administered as a single immunogen in 1 humans triggers robust, polyfunctional and selective effector memory T cell 2
2011
Immunization with recombinant DNA and modified vaccinia virus Ankara (MVA) vectors delivering PSCA and STEAP1 antigens inhibits prostate cancer progression
Vaccine·2010· 43 cited
Immunogenic Profiling in Mice of a HIV/AIDS Vaccine Candidate (MVA-B) Expressing Four HIV-1 Antigens and Potentiation by Specific Gene Deletions
PLoS ONE·2010· 81 citedOpen Access
Insertion of Vaccinia Virus C7L Host Range Gene into NYVAC-B Genome Potentiates Immune Responses against HIV-1 Antigens
PLoS ONE·2010· 71 citedOpen Access
Selective Induction of Host Genes by MVA-B, a Candidate Vaccine against HIV/AIDS
Journal of Virology·2010· 37 citedOpen Access
P02-04. Multimeric soluble CD40 ligand efficiently enhances HIV specific cellular immune responses during DNA prime and boost with attenuated poxvirus strains
Retrovirology·2009Open Access
P17-07. Insertion of a vaccinia virus host range (hr) gene into NYVAC-B genome potentiates immune responses against HIV-1 antigens
Retrovirology·2009Open Access
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Frequent Co-authors

Mariano Estéban(31), Carmen Gómez(20), Carlos Óscar S. Sorzano(9), Beatriz Perdiguero(8), Victoria Jiménez(8), Juan García‐Arriaza(7), Susana Guerra(5), José M. Gatell(5), Giuseppe Pantaleo(5), Eva Pérez-Jiménez(4), Elena Domingo-Gil(4), María Magdalena Gherardi(4), Felipe García(4), Magdalena Krupa(3), Luis A. López‐Fernández(3), Ralf Wagner(3), Peter Liljeström(3), Alberto C. Guardo(3), Rubén González-Sanz(3), Ernesto Mejías‐Pérez(3)