Margaret L. Shumate

Penn State Milton S. Hershey Medical Center — United States

Medicine · Health Sciences

13h-index485citations24works0.02yr avg
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Research Topics

Growth Hormone and Insulin-like Growth Factors(9), Clinical Nutrition and Gastroenterology(6), Liver Disease Diagnosis and Treatment(4), Wound Healing and Treatments(3), Muscle metabolism and nutrition(3)

Publications24 total

Skeletal muscle catabolism in trinitrobenzene sulfonic acid–induced murine colitis
Metabolism·2010· 16 citedOpen Access
Nuclear Factor-κB Mediates the Inhibitory Effects of Tumor Necrosis Factor-α on Growth Hormone-Inducible Gene Expression in Liver
Endocrinology·2008· 12 citedOpen Access
Nuclear Factor κB Mediates the Inhibitory Effects of Interleukin-1 on Growth Hormone-Inducible Gene Expression
The Journal of Trauma: Injury, Infection, and Critical Care·2008· 4 cited
Interleukin-6 inhibits growth hormone-mediated gene expression in hepatocytes
American Journal of Physiology-Gastrointestinal and Liver Physiology·2007· 34 cited
INHIBITION OF GROWTH HORMONE (GH)-INDUCED SPI 2.1 GENE EXPRESSION BY TUMOR NECROSIS FACTOR ALPHA (TNF??) INVOLVES NF-??B ACTIVATION
Shock·2006
Tumor necrosis factor inhibits growth hormone-mediated gene expression in hepatocytes
American Journal of Physiology-Gastrointestinal and Liver Physiology·2006· 22 cited
Hepatic growth hormone resistance during sepsis is associated with increased suppressors of cytokine signaling expression and impaired growth hormone signaling
Critical Care Medicine·2006· 44 cited
The Inhibitory Effects of Interleukin‐1 on Growth Hormone Action During Catabolic Illness
Vitamins and hormones·2006· 29 cited
Interleukin-1 inhibits the induction of insulin-like growth factor-I by growth hormone in CWSV-1 hepatocytes
American Journal of Physiology-Gastrointestinal and Liver Physiology·2005· 34 cited
PERVANADATE BLOCKS THE INHIBITORY EFFECTS OF TNF ON GH SIGNALING
Shock·2004· 1 cited
IL-1 INHIBITS THE INDUCTION OF IGF-I BY GH IN CWSV-1 HEPATOCYTES
Shock·2003
MECHANISMS OF GROWTH HORMONE RESISTANCE DURING ABDOMINAL SEPSIS.
Shock·2003
Capsaicin-sensitive nerves regulate the metabolic response to abdominal sepsis
Journal of Surgical Research·2003· 20 cited
Tumor necrosis factor mediates hepatic growth hormone resistance during sepsis
American Journal of Physiology-Endocrinology and Metabolism·2002· 60 cited
TUMOR NECROSIS FACTOR MEDIATES HEPATIC GROWTH HORMONE RESISTANCE DURING SEPSIS.
Shock·2002
Effects of Tumor Necrosis Factor-Binding Protein on Hepatic Protein Synthesis during Chronic Sepsis
Journal of Surgical Research·2000· 7 cited
Growth hormone does not attenuate the inhibitory effects of sepsis on wound healing
Wound Repair and Regeneration·2000· 13 cited
Interleukin-1 Receptor Antagonist Attenuates Tumor Necrosis Factor-Induced Alterations in Wound Breaking Strength
1999· 15 cited
Chronic Infusion of Interleukin 1 Induces Hyperlactatemia and Altered Regulation of Lactate Metabolism in Skeletal Muscle
Journal of Parenteral and Enteral Nutrition·1999· 19 cited
TNF-binding protein ameliorates inhibition of skeletal muscle protein synthesis during sepsis
American Journal of Physiology-Endocrinology and Metabolism·1999· 54 cited
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Frequent Co-authors

Robert N. Cooney(24), Charles H. Lang(11), George O. Maish(9), Thomas C. Vary(9), Gladys Yumet(9), Maithili Navaratnarajah(5), Tamer A. Ahmed(4), Mark D. Buzzelli(4), Douglas Bryant(3), H. Paul Ehrlich(3), Murali Nagarajan(3), Patrick Bryant(2), Tracie Gilpin(1), Cheng-Mao Lin(1), Scot R. Kimball(1), Rebecca Eckman(1), John B. Capen(1), Peter Rotwein(1), Patrick O’Neill(1), Frances J. Puleo(1)