Srigiridhar Kotamraju

Indian Institute of Chemical Technology — India

Chemistry · Physical Sciences

39h-index6.5kcitations92works6.22yr avg
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Research Topics

Synthesis and biological activity(16), Nitric Oxide and Endothelin Effects(12), Click Chemistry and Applications(8), Sirtuins and Resveratrol in Medicine(7), Electrochemical sensors and biosensors(6)

Publications92 total

Doxorubicin Resistance Reprograms Triple‐Negative Breast Cancer Cell Metabolism via the Fatty Acid β‐Oxidation (FAO)‐CD36 Regulatory Circuit: Relevance of Enhanced FAO on Tumor Cell Invasiveness
Molecular Carcinogenesis·2025
MTDH∆7-mediated mTOR activation drives doxorubicin resistance in triple-negative breast cancer: Relevance of mTORC1 inhibition on chemosensitization
Cellular Signalling·2025· 5 cited
SIRT1 promotes doxorubicin‐induced breast cancer drug resistance and tumor angiogenesis via regulating GSH‐mediated redox homeostasis
Molecular Carcinogenesis·2024· 10 cited
Mitochondria targeted esculetin administration improves insulin resistance and hyperglycemia-induced atherosclerosis in db/db mice
Journal of Molecular Medicine·2024· 2 cited
Mitochondria-targeted esculetin and metformin delay endothelial senescence by promoting fatty acid β-oxidation: Relevance in age-associated atherosclerosis
Mechanisms of Ageing and Development·2024· 14 cited
Correction to: Therapeutic efficacies of mitochondria‑targeted esculetin and metformin in the improvement of age‑associated atherosclerosis via regulating AMPK activation
GeroScience·2023· 1 citedOpen Access
Therapeutic efficacies of mitochondria-targeted esculetin and metformin in the improvement of age-associated atherosclerosis via regulating AMPK activation
GeroScience·2023· 20 citedOpen Access
Therapeutic efficacy of mitochondria-targeted esculetin in the improvement of NAFLD-NASH via modulating AMPK-SIRT1 axis
International Immunopharmacology·2023· 8 cited
<scp>DOT1L</scp> regulates <scp>MTDH</scp> ‐mediated angiogenesis in triple‐negative breast cancer: intermediacy of <scp>NF‐κB‐HIF1α</scp> axis
FEBS Journal·2022· 20 cited
Mitochondria-targeted esculetin mitigates atherosclerosis in the setting of aging via the modulation of SIRT1-mediated vascular cell senescence and mitochondrial function in Apoe mice
Atherosclerosis·2022· 42 cited
A functional and self-assembling octyl-phosphonium-tagged esculetin as an effective siRNA delivery agent
Chemical Communications·2021· 7 cited
sp<sup>3</sup>‐Rich Glycyrrhetinic Acid Analogues Using Late‐Stage Functionalization as Potential Breast Tumor Regressing Agents
ChemMedChem·2020· 6 cited
A novel metadherinΔ7 splice variant enhances triple negative breast cancer aggressiveness by modulating mitochondrial function via NFĸB-SIRT3 axis
Oncogene·2019· 36 cited
N‐end rule pathway inhibitor sensitizes cancer cells to antineoplastic agents by regulating XIAP and RAD21 protein expression
Journal of Cellular Biochemistry·2019· 9 cited
3‐(2‐(5‐Amino‐3‐aryl‐1 <i>H</i> ‐pyrazol‐1‐yl) thiazol‐4‐yl)‐2 <i>H</i> ‐chromen‐2‐ones as Potential Anticancer Agents: Synthesis, Anticancer Activity Evaluation and Molecular Docking Studies
ChemistrySelect·2019· 19 cited
Doxorubicin induces prostate cancer drug resistance by upregulation of ABCG4 through GSH depletion and CREB activation: Relevance of statins in chemosensitization
Molecular Carcinogenesis·2019· 36 cited
High Affinity Neutral Bodipy Fluorophores for Mitochondrial Tracking
ACS Medicinal Chemistry Letters·2018· 30 citedOpen Access
Recent trends in electrochemical biosensors of superoxide dismutases
Biosensors and Bioelectronics·2018· 58 citedOpen Access
Metformin treatment prevents SREBP2-mediated cholesterol uptake and improves lipid homeostasis during oxidative stress-induced atherosclerosis
Free Radical Biology and Medicine·2018· 59 cited
Novel 1,2,3‐Triazole‐Functionalized 1,2‐Benzothiazine 1,1‐Dioxide Derivatives: Regioselective Synthesis, Biological Evaluation and Docking Studies
ChemistrySelect·2018· 11 cited
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Frequent Co-authors

Joy Joseph(17), Balaraman Kalyanaraman(17), Santosh Karnewar(15), Shasi V. Kalivendi(14), Eugene A. Konorev(8), B. Kalyanaraman(7), Sathish Babu Vasamsetti(6), Anantha Koteswararao Kanugula(6), Tiesong Shang(5), C. Karunakaran(5), Praveen Neeli(5), Paradesi Naidu Gollavilli(5), Suwei Wang(4), Christopher R. Chitambar(4), Cecilia J. Hillard(4), Raja Gopoju(4), Jerald Mahesh Kumar(3), Shashi Kalivendi(3), Anuradha Dhanasekaran(3), Toshiyuki Matsunaga(3)