MyTrang Nguyen

University of North Carolina at Chapel Hill — United States

Medicine · Health Sciences

19h-index2.4kcitations33works12.72yr avg
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Research Topics

Inflammatory mediators and NSAID effects(10), Asthma and respiratory diseases(9), Inflammasome and immune disorders(6), Immune Response and Inflammation(5), Estrogen and related hormone effects(5)

Publications33 total

Pharmacological Analysis of NLRP3 Inflammasome Inhibitor Sodium [(1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl][(1-methyl-1<i>H</i>-pyrazol-4-yl)({[(2<i>S</i>)-oxolan-2-yl]methyl})sulfamoyl]azanide in Cellular and Mouse Models of Inflammation Provides a Translational Framework
ACS Pharmacology & Translational Science·2024· 7 citedOpen Access
Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases
Cell Reports·2024· 18 citedOpen Access
Target Cell Activation of a Structurally Novel NOD-Like Receptor Pyrin Domain-Containing Protein 3 Inhibitor NT-0796 Enhances Potency
Journal of Pharmacology and Experimental Therapeutics·2024· 13 citedOpen Access
Elarekibep (PRS-060/AZD1402), a new class of inhaled Anticalin medicine targeting IL-4Ra for type 2 endotype asthma
Journal of Allergy and Clinical Immunology·2022· 13 cited
PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth
UNC Libraries·2020Open Access
Genetic Loss of Murine Pyrin, the Familial Mediterranean Fever Protein, Increases Interleukin-1β Levels
UNC Libraries·2020Open Access
Receptors for prostaglandin E2 that regulate cellular immune responses in the mouse
UNC Libraries·2020Open Access
Transcellular biosynthesis contributes to the production of leukotrienes during inflammatory responses in vivo
UNC Libraries·2020Open Access
ONZIN deficiency attenuates contact hypersensitivity responses in mice
UNC Libraries·2020Open Access
Beyond detoxification: Pleiotropic functions of multiple glutathione S-transferase isoforms protect mice against a toxic electrophile
PLoS ONE·2019· 21 citedOpen Access
Abstract 503: Prostaglandin E2 produced by tumor cells or by the host tumor microenvironment is not completely abolished by aspirin or celecoxib and limits the ability of the host immune system to control tumor growth
Immunology·2019
Abstract 503: Prostaglandin E2 produced by tumor cells or by the host tumor microenvironment is not completely abolished by aspirin or celecoxib and limits the ability of the host immune system to control tumor growth
Cancer Research·2019· 2 cited
Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
Drug Metabolism and Disposition·2014· 18 citedOpen Access
Genetic Loss of Murine Pyrin, the Familial Mediterranean Fever Protein, Increases Interleukin-1β Levels
PLoS ONE·2012· 61 citedOpen Access
NLRP1-Dependent Pyroptosis Leads to Acute Lung Injury and Morbidity in Mice
The Journal of Immunology·2012· 273 citedOpen Access
PGE2 through the EP4 receptor controls smooth muscle gene expression patterns in the ductus arteriosus critical for remodeling at birth
Prostaglandins & Other Lipid Mediators·2012· 32 citedOpen Access
ONZIN deficiency attenuates contact hypersensitivity responses in mice
Immunology and Cell Biology·2012· 13 citedOpen Access
A major role for the EP4 receptor in regulation of renin
American Journal of Physiology-Renal Physiology·2011· 44 citedOpen Access
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia
The Journal of Experimental Medicine·2007· 41 citedOpen Access
Enhanced mast cell activation in mice deficient in the A2b adenosine receptor
The Journal of Experimental Medicine·2007· 82 citedOpen Access
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Frequent Co-authors

Beverly H. Koller(32), Martina Kovářová(9), John N. Snouwaert(8), Thomas M. Coffman(7), Leigh A. Jania(7), Stephen L. Tilley(6), Kenneth Coggins(6), Jennifer L. Goulet(6), Jenny P.‐Y. Ting(4), J Fabre(4), Estelle Riche(4), Steven Offenbacher(4), Laurent Audoly(3), Chandra Nataraj(3), Dennis W. Thomas(3), Roslyn B. Mannon(3), Pamela R. Hesker(3), Christopher A. Gabel(3), Jean-Etienne Fabre(2), Anne M. Latour(2)