David W. Speicher

The Wistar Institute — United States

Chemistry · Physical Sciences

86h-index28.5kcitations613works3.32yr avg
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Research Topics

Advanced Proteomics Techniques and Applications(96), Erythrocyte Function and Pathophysiology(66), Mass Spectrometry Techniques and Applications(60), Histone Deacetylase Inhibitors Research(54), Cancer, Hypoxia, and Metabolism(48)

Publications610 total

Supplementary Data Figures S1-S5 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2025Open Access
Supplementary Data Tables S1-S2 from Targeting UGCG Overcomes Resistance to Lysosomal Autophagy Inhibition
2025Open Access
Retraction Note: sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance
Nature·2025Open Access
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025Open Access
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025Open Access
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2025Open Access
Selective abrogation of S6K2 identifies lipid homeostasis as a survival vulnerability in MAPK inhibitor–resistant <i>NRAS</i> -mutant melanoma
Science Translational Medicine·2025· 2 citedOpen Access
Author Correction: Stromal changes in the aged lung induce an emergence from melanoma dormancy
Nature·2025· 3 citedOpen Access
S2903 Detection of Human Genomic DNA in Stool Samples From Seven Patients
The American Journal of Gastroenterology·2024
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Data from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Supplemental Figure 3 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Data from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Supplemental Figure 2 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Supplemental Figure 1 from Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
2024Open Access
Age-Related Increases in IGFBP2 Increase Melanoma Cell Invasion and Lipid Synthesis
Cancer Research Communications·2024· 12 citedOpen Access
Multiplexed serum biomarkers to discriminate nonviable and ectopic pregnancy
Fertility and Sterility·2024· 7 citedOpen Access
TXNRD1 drives the innate immune response in senescent cells with implications for age-associated inflammation
Nature Aging·2024· 26 citedOpen Access
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Frequent Co-authors

Hsin‐Yao Tang(10), Andrew V. Kossenkov(10), Xiaowei Xu(7), Meenhard Herlyn(6), Qin Liu(6), Rugang Zhang(5), Ronen Marmorstein(5), Dennis E. Discher(4), Frank J. Rauscher(4), Katherine M. Aird(4), D. Schultz(4), Ashani T. Weeraratna(4), Lucia R. Languino(4), Kaye D. Speicher(4), Benjamin G. Bitler(3), Marie R. Webster(3), Gretchen M. Alicea(3), Young Chan Chae(3), Dario C. Altieri(3), V. Marchesi(3)