Harold E. Layton

Duke University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

30h-index2.3kcitations81works0.02yr avg
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Research Topics

Ion Transport and Channel Regulation(36), Electrolyte and hormonal disorders(17), Nonlinear Dynamics and Pattern Formation(15), Dialysis and Renal Disease Management(8), Urinary Bladder and Prostate Research(7)

Publications80 total

A computational model of epithelial solute and water transport along a human nephron
PLoS Computational Biology·2019· 56 citedOpen Access
Functional implications of sexual dimorphism of transporter patterns along the rat proximal tubule: modeling and analysis
American Journal of Physiology-Renal Physiology·2018· 83 citedOpen Access
Heterodyning in Tubuloglomerular Feedback Induced Oscillations in Coupled Model Nephrons
The FASEB Journal·2016
How Is Urine Concentrated by the Renal Inner Medulla?1
Contributions to nephrology·2015· 35 cited
Advances in Understanding the Urine-Concentrating Mechanism
Annual Review of Physiology·2013· 111 citedOpen Access
Urine-Concentrating Mechanism in the Inner Medulla
Clinical Journal of the American Society of Nephrology·2013· 97 citedOpen Access
The Urine Concentrating Mechanism and Urea Transporters
Elsevier eBooks·2012· 45 cited
Transport efficiency and workload distribution in a mathematical model of the thick ascending limb
American Journal of Physiology-Renal Physiology·2012· 19 citedOpen Access
Fluid dilution and efficiency of Na<sup>+</sup>transport in a mathematical model of a thick ascending limb cell
American Journal of Physiology-Renal Physiology·2012· 7 citedOpen Access
The Physiology of Water Homeostasis
2012· 1 cited
Signal transduction in a compliant thick ascending limb
American Journal of Physiology-Renal Physiology·2012· 9 citedOpen Access
Urine Concentration and Dilution
Elsevier eBooks·2012· 40 cited
List of Contributors
Elsevier eBooks·2012· 1 cited
Countercurrent multiplication may not explain the axial osmolality gradient in the outer medulla of the rat kidney
American Journal of Physiology-Renal Physiology·2011· 24 citedOpen Access
Propagation of vasoconstrictive responses in a mathematical model of the rat afferent arteriole
The FASEB Journal·2011
Efficiency of sodium transport in a model of the Thick Ascending Limb (TAL)
The FASEB Journal·2011
Dynamical Properties of the Thick Ascending Limb (TAL): A Modeling Study
The FASEB Journal·2011
Feedback-mediated dynamics in a model of coupled nephrons with compliant thick ascending limbs
Mathematical Biosciences·2011· 9 citedOpen Access
A mathematical model of the myogenic response to systolic pressure in the afferent arteriole
American Journal of Physiology-Renal Physiology·2010· 51 citedOpen Access
Urine concentrating mechanism in the inner medulla of the mammalian kidney: role of three‐dimensional architecture
Acta Physiologica·2010· 41 citedOpen Access
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Frequent Co-authors

Anita T. Layton(23), Leon C. Moore(14), E. Bruce Pitman(10), William H. Dantzler(6), Thomas L. Pannabecker(6), Jeff M. Sands(5), L. C. Moore(3), M. A. Knepper(2), John Davies(2), E BRUCEPITMAN(2), Sophie Thomas(2), Kayne M. Arthurs(1), Charles S. Peskin(1), Qianyi Li(1), Alicia A. McDonough(1), Chung‐Lin Chou(1), Jing Chen(1), Ioannis Sgouralis(1), Robert A. Fenton(1), Roman M. Zaritski(1)