Zachary Glass

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index2.3kcitations29works8.02yr avg
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Research Topics

RNA Interference and Gene Delivery(13), CRISPR and Genetic Engineering(10), Advanced biosensing and bioanalysis techniques(6), Lipid Membrane Structure and Behavior(4), Virus-based gene therapy research(4)

Publications29 total

An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves precise and durable liver editing in nonclinical studies
Atherosclerosis·2024· 8 citedOpen Access
An investigational in vivo base editing medicine targeting ANGPTL3, VERVE-201, achieves potent and LDLR-independent liver editing in mouse models
European Heart Journal·2023· 9 citedOpen Access
Chemical Modification of Proteins and Their Intracellular Delivery Using Lipidoid Nanoparticles
Methods in molecular biology·2022· 2 cited
In situ cancer vaccination using lipidoid nanoparticles
Science Advances·2021· 114 citedOpen Access
Lipid nanoparticle-mediated codelivery of Cas9 mRNA and single-guide RNA achieves liver-specific in vivo genome editing of<i>Angptl3</i>
Proceedings of the National Academy of Sciences·2021· 355 citedOpen Access
Enhanced protein degradation by intracellular delivery of pre-fused PROTACs using lipid-like nanoparticles
Journal of Controlled Release·2020· 60 citedOpen Access
mRNA Delivery Using Bioreducible Lipidoid Nanoparticles Facilitates Neural Differentiation of Human Mesenchymal Stem Cells
Advanced Healthcare Materials·2020· 34 cited
Neurotransmitter-derived lipidoids (NT-lipidoids) for enhanced brain delivery through intravenous injection
Science Advances·2020· 195 citedOpen Access
Imidazole‐Based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes
Angewandte Chemie International Edition·2020· 165 cited
Imidazole‐Based Synthetic Lipidoids for In Vivo mRNA Delivery into Primary T Lymphocytes
Angewandte Chemie·2020· 11 cited
Protein and mRNA Delivery Enabled by Cholesteryl‐Based Biodegradable Lipidoid Nanoparticles
Angewandte Chemie International Edition·2020· 69 cited
Protein and mRNA Delivery Enabled by Cholesteryl‐Based Biodegradable Lipidoid Nanoparticles
Angewandte Chemie·2020· 32 citedOpen Access
Ex vivo cell-based CRISPR/Cas9 genome editing for therapeutic applications
Biomaterials·2020· 97 citedOpen Access
<i>In Vitro</i> and <i>In Vivo</i> Study of Amphotericin B Formulation with Quaternized Bioreducible Lipidoids
ACS Biomaterials Science & Engineering·2020· 19 cited
Nonviral Nanoparticles for CRISPR-Based Genome Editing: Is It Just a Simple Adaption of What Have Been Developed for Nucleic Acid Delivery?
Biomacromolecules·2019· 30 citedOpen Access
Integrating Combinatorial Lipid Nanoparticle and Chemically Modified Protein for Intracellular Delivery and Genome Editing
Accounts of Chemical Research·2018· 122 citedOpen Access
Intracellular delivery and biodistribution study of CRISPR/Cas9 ribonucleoprotein loaded bioreducible lipidoid nanoparticles
Biomaterials Science·2018· 93 cited
Rescued from the fate of neurological disorder
Nature Biomedical Engineering·2018· 4 cited
Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins
Biomaterials·2018· 84 cited
Engineering the Delivery System for CRISPR-Based Genome Editing
Trends in biotechnology·2018· 331 citedOpen Access
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Frequent Co-authors

Qiaobing Xu(20), Yamin Li(14), Jinjin Chen(10), Min Qiu(6), Xuewei Zhao(6), Liu Yang(5), Yingjie Yu(4), Feihe Ma(3), Xuehui Rui(2), Zhongfeng Ye(2), Ming Wang(2), Justin Bolinger(2), Nicola Shi(2), Liu Yang(2), June‐Hee Park(2), Kasim Sayed(2), Tatyana V. Michurina(2), Grigori Enikolopov(2), Rachel Jarvis(2), Kuixin Zhu(2)