David W. Self

The University of Texas Southwestern Medical Center — United States

Neuroscience · Life Sciences

53h-index16.3kcitations103works0.02yr avg
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Research Topics

Neurotransmitter Receptor Influence on Behavior(74), Receptor Mechanisms and Signaling(44), Neuroscience and Neuropharmacology Research(39), Memory and Neural Mechanisms(11), Neuropeptides and Animal Physiology(11)

Publications103 total

Cocaine-Induced Synaptic Redistribution of NMDARs in Striatal Neurons Alters NMDAR-Dependent Signal Transduction
Frontiers in Neuroscience·2020· 6 citedOpen Access
Knockdown of the histone di-methyltransferase G9a in nucleus accumbens shell decreases cocaine self-administration, stress-induced reinstatement, and anxiety
Neuropsychopharmacology·2018· 38 citedOpen Access
Viral Vector Targeting of Specific Brain Circuits in Neuropsychiatric Disease Models
Pharmacology Biochemistry and Behavior·2018
Overexpression of the Histone Dimethyltransferase G9a in Nucleus Accumbens Shell Increases Cocaine Self-Administration, Stress-Induced Reinstatement, and Anxiety
Journal of Neuroscience·2017· 58 citedOpen Access
Inactivation of NMDA Receptors in the Ventral Tegmental Area during Cocaine Self-Administration Prevents GluA1 Upregulation but with Paradoxical Increases in Cocaine-Seeking Behavior
Journal of Neuroscience·2017· 9 citedOpen Access
HDAC5 and Its Target Gene, Npas4, Function in the Nucleus Accumbens to Regulate Cocaine-Conditioned Behaviors
Neuron·2017· 122 citedOpen Access
BDNF-TrkB controls cocaine-induced dendritic spines in rodent nucleus accumbens dissociated from increases in addictive behaviors
Proceedings of the National Academy of Sciences·2017· 41 citedOpen Access
Incubation of cue-induced reinstatement of cocaine, but not sucrose, seeking in C57BL/6J mice
Pharmacology Biochemistry and Behavior·2017· 20 citedOpen Access
It's only a matter of time: longevity of cocaine-induced changes in dendritic spine density in the nucleus accumbens
Current Opinion in Behavioral Sciences·2016· 17 citedOpen Access
Optogenetic Stimulation of Accumbens Shell or Shell Projections to Lateral Hypothalamus Produce Differential Effects on the Motivation for Cocaine
Journal of Neuroscience·2015· 43 citedOpen Access
Direct Regulation of Diurnal Drd3 Expression and Cocaine Reward by NPAS2
Biological Psychiatry·2014· 108 citedOpen Access
Diminished Role for Dopamine D1 Receptors in Cocaine Addiction?
Biological Psychiatry·2014· 12 citedOpen Access
ΔFosB Induction in Striatal Medium Spiny Neuron Subtypes in Response to Chronic Pharmacological, Emotional, and Optogenetic Stimuli
Journal of Neuroscience·2013· 245 citedOpen Access
Adenosine A1 and Dopamine D1 Receptor Regulation of AMPA Receptor Phosphorylation and Cocaine-Seeking Behavior
Neuropsychopharmacology·2013· 34 citedOpen Access
Cocaine self-administration behaviors in ClockΔ19 mice
Psychopharmacology·2012· 82 citedOpen Access
Overexpression of CREB in the Nucleus Accumbens Shell Increases Cocaine Reinforcement in Self-Administering Rats
Journal of Neuroscience·2011· 130 citedOpen Access
Reinforcement-Related Regulation of AMPA Glutamate Receptor Subunits in the Ventral Tegmental Area Enhances Motivation for Cocaine
Journal of Neuroscience·2011· 43 citedOpen Access
Emergence of context-associated GluR1 and ERK phosphorylation in the nucleus accumbens core during withdrawal from cocaine self-administration
Addiction Biology·2011· 34 citedOpen Access
Striatal Signal Transduction and Drug Addiction
Frontiers in Neuroanatomy·2011· 42 citedOpen Access
Stress-Related Receptor Targets for Cocaine Addiction
Biological Psychiatry·2010· 2 cited
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Frequent Co-authors

Eric J. Nestler(26), Danielle Graham(8), Rachael L. Neve(8), Ryan K. Bachtell(8), Scott J. Russo(6), Scott Edwards(6), Diana Simmons(6), William Renthal(5), Ralph Dileone(5), Michel Barrot(5), Erin B. Larson(5), Arvind Kumar(4), Amelia J. Eisch(4), Carlos A. Bolaños(4), Lisa M. Monteggia(4), Kwang-Ho Choi(4), David E. H. Theobald(4), Ronald S. Duman(4), Linda I. Perrotti(4), Vaishnav Krishnan(3)