Christopher O. Barnes

Chan Zuckerberg Initiative (United States) — United States

Medicine · Health Sciences

41h-index14.3kcitations115works5.82yr avg
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Research Topics

SARS-CoV-2 and COVID-19 Research(45), Monoclonal and Polyclonal Antibodies Research(25), HIV Research and Treatment(22), Animal Virus Infections Studies(14), COVID-19 Clinical Research Studies(12)

Publications115 total

Oriented Multivalent Display Drives Consistent Serum Immunodominance to the Ebola Virus Glycoprotein
ACS Central Science·2026Open Access
Human antibodies against West Nile virus and related Orthoflaviviruses 9100
The Journal of Immunology·2025Open Access
Human Coronavirus HKU1 Neutralizing Monoclonal Antibodies Target Diverse Epitopes Within and Around the TMPRSS2 Receptor Binding Site
2025Open Access
Structure-guided design of native-like HIV Env Single Chain Trimers for enhanced stability, immunogenicity, and versatile vaccine delivery
2025Open Access
Juneteenth in STEMM and the barriers to equitable science
UNC Libraries·2025Open Access
Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines
Advanced Science·2025· 7 citedOpen Access
Bispecific antibodies targeting the N-terminal and receptor binding domains potently neutralize SARS-CoV-2 variants of concern
Science Translational Medicine·2025· 12 citedOpen Access
BPS2025 - Structure-guided engineering of flavivirus nonstructural protein 1
Biophysical Journal·2025
BPS2025 - Structural design and characterization of prefusion-stabilized coronavirus S2 proteins in complex with antibodies
Biophysical Journal·2025
Discovery and engineering of the antibody response to a prominent skin commensal
Nature·2024· 32 citedOpen Access
Structural basis of transcription: RNA polymerase II substrate binding and metal coordination using a free-electron laser
Proceedings of the National Academy of Sciences·2024· 13 citedOpen Access
Bispecific antibodies with broad neutralization potency against SARS-CoV-2 variants of concern
2024· 2 citedOpen Access
Sustained Vaccine Exposure Elicits More Rapid, Consistent, and Broad Humoral Immune Responses to Multivalent Influenza Vaccines
2024· 4 citedOpen Access
Author Correction: SARS-CoV-2 neutralizing antibody structures inform therapeutic strategies
Nature·2024· 4 citedOpen Access
Exploring the structural basis of antibody-envelope interactions and the significance of glycan arrays in epitope recognition
Biophysical Journal·2024Open Access
Exploring the structural basis of cross-reactive TBEV monoclonal antibodies
Biophysical Journal·2024
Structural insights into cross-reactive antibodies recognizing the N-terminal and receptor binding domains of the SARS-CoV-2 spike glycoprotein
Biophysical Journal·2024
Discovery and engineering of the antibody response against a prominent skin commensal
2024· 2 citedOpen Access
Vaccine design via antigen reorientation
Nature Chemical Biology·2024· 35 citedOpen Access
A Deep-Learning Data-Driven Approach for Reducing FPGA Routing Runtimes
2023· 2 cited
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Frequent Co-authors

Pamela J. Björkman(28), Michel C. Nussenzweig(26), Frauke Muecksch(18), Paul D. Bieniasz(18), Théodora Hatziioannou(17), Christian Gaebler(16), Fabian Schmidt(16), Marina Caskey(16), Zijun Wang(15), Shlomo Finkin(14), Anthony P. West(14), Thiago Y. Oliveira(13), Yiska Weisblum(13), Davide F. Robbiani(12), Anna Gazumyan(12), Katrina G. Millard(12), Melissa Cipolla(12), Víctor Ramos(12), Kathryn E. Huey‐Tubman(12), Alice Cho(11)