Francesca Virginia Bruschi

Medical University of Vienna — Austria

Medicine · Health Sciences

11h-index587citations22works0.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Liver Disease Diagnosis and Treatment(19), Liver Diseases and Immunity(6), Diet, Metabolism, and Disease(6), Liver physiology and pathology(5), Lipid metabolism and biosynthesis(5)

Publications22 total

Absence of Adiponutrin (PNPLA3) and Monoacylglycerol Lipase Synergistically Increases Weight Gain and Aggravates Steatohepatitis in Mice
International Journal of Molecular Sciences·2021· 6 citedOpen Access
PNPLA3 I148M Up-Regulates Hedgehog and Yap Signaling in Human Hepatic Stellate Cells
International Journal of Molecular Sciences·2020· 26 citedOpen Access
Issue Cover
Liver International·2020
The Role of Metabolic Lipases in the Pathogenesis and Management of Liver Disease
Hepatology·2020· 44 citedOpen Access
Metabolic regulation of hepatic PNPLA3 expression and severity of liver fibrosis in patients with NASH
Liver International·2020· 30 citedOpen Access
Monoacylglycerol Lipase Inhibition Protects From Liver Injury in Mouse Models of Sclerosing Cholangitis
Hepatology·2019· 31 citedOpen Access
PNPLA3 I148M Variant Impairs Liver X Receptor Signaling and Cholesterol Homeostasis in Human Hepatic Stellate Cells
Hepatology Communications·2019· 35 citedOpen Access
Lack of monoacylglycerol lipase prevents hepatic steatosis by favoring lipid storage in adipose tissue and intestinal malabsorption
Journal of Lipid Research·2019· 36 citedOpen Access
THU-023-Monoacylglycerol lipase inhibition protects from hepatic inflammation and fibrosis in mouse models of sclerosing cholangitis
Journal of Hepatology·2019· 3 cited
PS-092-Lack of monoacylglycerol lipase protects from MCD-induced hepatic inflammation and fibrosis
Journal of Hepatology·2019
FRI-348-Monoacylglycerol lipase deletion protects against obesity-induced hepatic steatosis via PPARg regulation in adipose tissue and fatty acid malabsorption in the intestine
Journal of Hepatology·2019
Mice Lacking Monoacylglycerol Lipase Are Protected from Hepatic Inflammation and Biliary Fibrosis in Ddc-Induced Sclerosing Cholangitis.
Data Archiving and Networked Services (DANS)·2018
Nuclear Receptor Regulation of Aquaglyceroporins in Metabolic Organs
International Journal of Molecular Sciences·2018· 14 citedOpen Access
The I148M PNPLA3 impairs LXR signaling and cholesterol metabolism in human hepatic stellate cells
Journal of Hepatology·2018
PNPLA3 expression and its impact on the liver: current perspectives
Hepatic Medicine Evidence and Research·2017· 77 citedOpen Access
AQP3 is regulated by PPARγ and JNK in hepatic stellate cells carrying PNPLA3 I148M
Scientific Reports·2017· 18 citedOpen Access
Adiponectin regulates AQP3 via PPARα in human hepatic stellate cells
Biochemical and Biophysical Research Communications·2017· 24 citedOpen Access
The genetic PNPLA3 variant I148M promotes liver fibrosis development by enhancing inflammatory and fibrogenic properties of human hepatic stellate cells / submitted by Francesca Virginia Bruschi, MSc
2017
The PNPLA3 I148M variant modulates the fibrogenic phenotype of human hepatic stellate cells
Hepatology·2017· 243 citedOpen Access
The I148M PNPLA3 variant is a novel key player modulating the proinflammatory and profibrogenic phenotype of human hepatic stellate cells
Journal of Hepatology·2017
page 1 of 2Next →

Frequent Co-authors

Matteo Tardelli(20), Michael Trauner(20), Thierry Claudel(18), Nicole Auer(6), Victoria Kunczer(6), Tatjana Stojaković(6), Sophie Lotersztajn(6), Claudia Fuchs(5), Thomas M. Stulnig(4), Fabio Marra(4), Onne A. H. O. Ronda(4), Merima Herac(4), Hubert Scharnagl(3), Robert Zimmermann(3), Henkjan J. Verkade(3), Aı̈da Habib(2), Patrick Starlinger(2), Verónica Moreno‐Viedma(2), A. Caligiuri(2), Alessandra Caligiuri(1)