David C.S. Huang

The University of Melbourne — Australia

Medicine · Health Sciences

101h-index45.2kcitations576works0.42yr avg
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Research Topics

Cancer-related Molecular Pathways(191), Cell death mechanisms and regulation(144), Chronic Lymphocytic Leukemia Research(63), RNA Interference and Gene Delivery(50), Ubiquitin and proteasome pathways(35)

Publications575 total

Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
2025· 1 citedOpen Access
Author response: Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
2025Open Access
Pseudo-thrombotic microangiopathy secondary to severe vitamin B12 deficiency: A case series
Blood·2025Open Access
Truncated CMV2bN43 enhances virus-induced gene silencing in pepper by retaining systemic but not local silencing suppression
Plant Methods·2025Open Access
Author response: Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
2025Open Access
Pharmacologic inhibition of BAF chromatin remodeling complexes as a therapeutic approach to transcription factor-dependent cancers
2025Open Access
Structural and functional basis of PU.1-BAF interaction enables targeting of lineage-specific transcription
2025· 1 cited
384 | PROGNOSTIC AND FUNCTIONAL IMPACT OF EGF‐JAK/STAT PATHWAY MUTATIONS IN ANGIOIMMUNOBLASTIC T‐CELL LYMPHOMA
Hematological Oncology·2025Open Access
ZMYND8 Reads H3K36me2 to Activate CEBPE Transcription and Suppress Multiple Myeloma Progression through the Inhibition of Adaptive UPR Pathways
Advanced Science·2025· 2 citedOpen Access
Re-appraising assays on permeabilized blood cancer cells testing venetoclax or other BH3 mimetic agents selectively targeting pro-survival BCL2 proteins
Cell Death and Differentiation·2025· 1 citedOpen Access
NONO interacts with nuclear PKM2 and directs histone H3 phosphorylation to promote triple-negative breast cancer metastasis
Journal of Experimental & Clinical Cancer Research·2025· 9 citedOpen Access
Differential regulation of BAX and BAK apoptotic activity revealed by small molecules
Science Advances·2025· 6 citedOpen Access
Single-cell Rapid Capture Hybridization sequencing reliably detects isoform usage and coding mutations in targeted genes
Genome Research·2025· 6 citedOpen Access
Computational Design of a Hepatitis B Virus Vaccine Using Multiple Sequence Alignment and Modeller v10.5 for 3D Protein Structure Prediction
2025Open Access
“Comprehensive Analysis of Factors Influencing Recurrence and Survival in Glioblastoma: Implications for Treatment Strategies”: A Single Center Study
Journal of Molecular Pathology·2024Open Access
PATH-51. CENTRAL NERVOUS SYSTEM METASTASES ARE GENOMICALLY DIVERGENT FROM THEIR RESPECTIVE EXTRACRANIAL SITES
Neuro-Oncology·2024Open Access
NONO directs PKM2-mediated H3T11ph to promote triple-negative breast cancer metastasis by activating SERPINE1 expression
2024Open Access
Venetoclax dose escalation rapidly activates a BAFF/BCL-2 survival axis in chronic lymphocytic leukemia
Blood·2024· 8 citedOpen Access
Acquired <i>BCL2</i> variants associated with venetoclax resistance in acute myeloid leukemia
Blood Advances·2024· 9 citedOpen Access
Differential regulation of BAX and BAK apoptotic activity revealed by a novel small molecule
2024
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Frequent Co-authors

Andreas Strasser(16), Andrew W. Roberts(13), Jerry M. Adams(10), Peter E. Czabotar(9), Peter M. Colman(7), Philippe Bouillet(7), Simon N. Willis(6), Andrew H. Wei(6), Mark F. van Delft(6), Benjamin T. Kile(6), Lorraine A. O’Reilly(6), Kylie D. Mason(5), Catherine L. Day(5), Suzanne Cory(5), Hamsa Puthalakath(5), Guillaume Lessène(5), Wayne J. Fairbrother(4), John F. Seymour(4), Brian J. Smith(4), Jamie I. Fletcher(4)