Claudio Realini

Swiss Institute for Regenerative Medicine — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

22h-index2.4kcitations34works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(16), PARP inhibition in cancer therapy(9), DNA Repair Mechanisms(8), Peptidase Inhibition and Analysis(7), Cancer therapeutics and mechanisms(6)

Publications34 total

Adult Human Adipose Tissue Contains Several Types of Multipotent Cells
Journal of Cardiovascular Translational Research·2011· 90 cited
Use of RNA Interference and Complementation To Study the Function of the <i>Drosophila</i> and Human 26S Proteasome Subunit S13
Molecular and Cellular Biology·2003· 67 citedOpen Access
Sequence of Crm1/exportin 1 mutant alleles reveals critical sites associated with multidrug resistance
Current Genetics·2001· 3 cited
Analysis ofFas/CD95 gene somatic mutations in ovarian cancer cell lines
International Journal of Cancer·2000· 6 citedOpen Access
Analysis of Fas/CD95 gene somatic mutations in ovarian cancer cell lines
International Journal of Cancer·2000
Lack of CD95/FAS gene somatic mutations in extranodal, nodal and splenic marginal zone B cell lymphomas
Leukemia·2000· 25 citedOpen Access
Sequence of crm1 mutant alleles in fission yeast reveals critical sites associated with multidrug resistance that are conserved in human CRM1.
Oxford University Research Archive (ORA) (University of Oxford)·2000
The proteasome activator 11 S REG (PA28) and Class I antigen presentation
Biochemical Journal·1999· 263 citedOpen Access
Intracellular Localization of Proteasomal Degradation of a Viral Antigen
The Journal of Cell Biology·1999· 211 citedOpen Access
Proteasome Activator 11S REG or PA28:  Recombinant REGα/REGβ Hetero-oligomers Are Heptamers<sup>1</sup>
Biochemistry·1999· 108 cited
Proteasome Activation by REG Molecules Lacking Homolog-specific Inserts
Journal of Biological Chemistry·1998· 31 citedOpen Access
Identification of an activation region in the proteasome activator REGα
Proceedings of the National Academy of Sciences·1998· 92 citedOpen Access
Structure of the proteasome activator REGα (PA28α)
Nature·1997· 186 cited
The proteasome 11S regulator subunit REGα (PA28α) is a heptamer
Protein Science·1997· 35 citedOpen Access
Characterization of Recombinant REGα, REGβ, and REGγ Proteasome Activators
Journal of Biological Chemistry·1997· 167 citedOpen Access
Potential Immunocompetence of Proteolytic Fragments Produced by Proteasomes before Evolution of the Vertebrate Immune System
The Journal of Experimental Medicine·1997· 83 citedOpen Access
Potential immunocompetence of proteolytic fragments produced by proteasomes before evolution of the vertebrate immune system
Immunology Letters·1997· 1 cited
Characterization of Recombinant REGa, REGb, and REGg Proteasome Activators*
1997· 6 cited
Proposed Role of a γ-Interferon Inducible Proteasome-Regulator in Antigen Presentation
Advances in experimental medicine and biology·1996· 6 cited
Human lymphoblast and erythrocyte multicatalytic proteases: differential peptidase activities and responses to the 11S regulator
FEBS Letters·1995· 43 cited
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Frequent Co-authors

Martin Rechsteiner(15), Felix R. Althaus(11), Phyllis L. Panzeter(9), Hanspeter Naegeli(6), Christopher P. Hill(5), Maria Malanga(5), Stefania Carobbio(5), Franco Cavalli(5), Steven C. Johnston(4), Liane Höfferer(4), Hanna E. Kleczkowska(4), Zhiguo Zhang(3), Christopher C. Jensen(3), Francesco Bertoni(3), Annarita Conconi(3), Emanuele Zucca(3), Georg A. Mathis(3), Pius Loetscher(3), Vicença Ustrell(2), J. Randolph Knowlton(2)