Kenneth M. Murphy

Immunology and Microbiology · Life Sciences

122h-index72.7kcitations465works7.82yr avg
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Research Topics

Immune Cell Function and Interaction(216), T-cell and B-cell Immunology(207), Immunotherapy and Immune Responses(177), Cytokine Signaling Pathways and Interactions(38), Immune Response and Inflammation(35)

Publications463 total

CD8+ T cells are primed by cDC1 and exacerbate tau-mediated neurodegeneration
2026
Transcription factor Maf promotes expression of repressor Zeb2 to drive microglia development in primitive hematopoiesis
Immunity·2025Open Access
WDFY4-dependent cross-presentation proceeds via a vacuolar antigen-processing route
Proceedings of the National Academy of Sciences·2025Open Access
The Making of a <scp>cDC1</scp> : Precision Programming of Progenitor Potential
Immunological Reviews·2025
Supplementary Data from The Conventional Dendritic Cell 1 Subset Primes CD8&lt;sup&gt;+&lt;/sup&gt; T Cells and Traffics Tumor Antigen to Drive Antitumor Immunity in the Brain
2025Open Access
Shared pathway of WDFY4-dependent cross-presentation by cDC1 and cDC2 4535
The Journal of Immunology·2025Open Access
S. aureus exposure during cutaneous antigen sensitization causes basophil- and interleukin-4-dependent exaggerated food anaphylaxis
Immunity·2025· 3 citedOpen Access
A Validated Regulatory Network for Th17 Cell Specification
Cell·2025
ID2 secures cDC1 specification by antagonizing E proteins at a pleiotropic Zeb2 enhancer
2025Open Access
Combined Flt3L and CD40 agonism restores dendritic cell–driven T cell immunity in pancreatic cancer
Science Immunology·2025· 6 cited
Type 1 classical dendritic cells govern long-term cardiac allograft acceptance
Journal of Clinical Investigation·2025· 2 citedOpen Access
Physical Health Monitoring of Patients Prescribed Depot Antipsychotic Medication and Clozapine in the North-West Edinburgh Community Mental Health Team
BJPsych Open·2025Open Access
cDC1s Promote Atherosclerosis via Local Immunity and Are Targetable for Therapy
Circulation Research·2025· 3 citedOpen Access
C/EBPα activates <i>Irf8</i> expression in myeloid progenitors at the +56-kb enhancer to initiate cDC1 development
Science Immunology·2025· 6 cited
“What’s in a name?” Clarifying the identity of RORγt+ antigen-presenting cells
The Journal of Experimental Medicine·2025· 3 citedOpen Access
Atopic skin inflammation promotes systemic anaphylactic responses via IL-13 signaling in conventional dendritic cells.
2025Open Access
Shared pathway of WDFY4-dependent cross-presentation of immune complexes by cDC1 and cDC2
The Journal of Experimental Medicine·2025· 9 citedOpen Access
Identification of antigen-presenting cell–T cell interactions driving immune responses to food
Science·2024· 51 citedOpen Access
Type I interferon signaling in dendritic cells limits direct antigen presentation and CD8 <sup>+</sup> T cell responses against an arthritogenic alphavirus
mBio·2024· 8 citedOpen Access
Optimization of the Irf8 +32-kb enhancer disrupts dendritic cell lineage segregation
Nature Immunology·2024· 7 citedOpen Access
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Frequent Co-authors

Theresa L. Murphy(10), Theresa L. Murphy(10), Anne O’Garra(8), Ansuman T. Satpathy(6), Xiaodi Wu(6), Kai Hildner(5), Brian T. Edelson(5), Robert D. Schreiber(5), Roxane Tussiwand(5), Wumesh KC(5), Nicole M. Kretzer(5), Chyi‐Song Hsieh(4), Masako Kohyama(4), Nancy Hosken(4), Wenjun Ouyang(4), Jörn C. Albring(4), Carlos G. Briseño(4), Casey T. Weaver(3), S E Macatonia(3), Maya Gavrieli(3)