Fredrik Almqvist

Umeå University — Sweden

Biochemistry, Genetics and Molecular Biology · Life Sciences

42h-index5.2kcitations208works1.52yr avg
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Research Topics

Chemical Synthesis and Analysis(28), Synthesis of heterocyclic compounds(21), Asymmetric Synthesis and Catalysis(19), Catalytic C–H Functionalization Methods(16), Parkinson's Disease Mechanisms and Treatments(15)

Publications208 total

Metabolic rewiring of isoniazid sensitivity in <i>Mycobacterium tuberculosis</i>
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
RACK1A positively regulates opening of the apical hook in <i>Arabidopsis thaliana</i> via suppression of its auxin response gradient
Proceedings of the National Academy of Sciences·2025· 1 citedOpen Access
Intra‐striatal infusion of the small molecule alpha‐synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV‐alpha‐synuclein rat model
European Journal of Neuroscience·2024Open Access
Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat <i>Streptococcus pyogenes</i> skin and soft tissue infection
Science Advances·2024· 8 citedOpen Access
Author response for "Intra‐striatal infusion of the small molecule alpha‐synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV‐alpha‐synuclein rat model"
2024
Author response for "Intra‐striatal infusion of the small molecule alpha‐synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV‐alpha‐synuclein rat model"
2024
Author response for "Intra‐striatal infusion of the small molecule alpha‐synuclein aggregator, FN075, does not enhance parkinsonism in a subclinical AAV‐alpha‐synuclein rat model"
2024
Intra-striatal infusion of the small molecule alpha-synuclein aggregator, FN075, fails to enhance Parkinsonism in a subclinical AAV-alpha-synuclein rat model.
2024Open Access
Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant <i>Mycobacterium tuberculosis</i>
mBio·2024· 5 citedOpen Access
Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat <i>Streptococcus pyogenes</i> skin and soft tissue infection
2024Open Access
Structural insights into CodY activation and DNA recognition
Nucleic Acids Research·2023· 4 citedOpen Access
A Highly Substituted Ring-Fused 2-Pyridone Compound Targeting PrfA and the Efflux Regulator BrtA in Listeria monocytogenes
mBio·2023· 6 citedOpen Access
Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug resistant <i>Mycobacterium tuberculosis</i>
2023· 1 citedOpen Access
Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics
Proceedings of the National Academy of Sciences·2022· 13 citedOpen Access
Complete Genome Sequence of the Uropathogenic Methicillin-Resistant Staphylococcus aureus Strain MRSA-1369
Microbiology Resource Announcements·2022· 2 citedOpen Access
THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates
Proceedings of the National Academy of Sciences·2021· 22 citedOpen Access
The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models
Biomolecules·2021· 8 citedOpen Access
A 2-Pyridone Amide Inhibitor of Transcriptional Activity in Chlamydia trachomatis
Antimicrobial Agents and Chemotherapy·2021· 6 citedOpen Access
An efficient and scalable synthesis of thiazolo ring fused 2-pyridones using flow chemistry
ARKIVOC·2021Open Access
Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c
Scientific Reports·2021· 12 citedOpen Access
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Frequent Co-authors

Scott J. Hultgren(15), Erik Chorell(13), Jerome S. Pinkner(12), Veronica Åberg(8), Matthew R. Chapman(8), Hans Emtenäs(6), Hans Andersson(6), Roger Olsson(6), James A. D. Good(6), Christoffer Bengtsson(6), Mattias Hedenström(5), Pernilla Wittung‐Stafshede(5), Margery L. Evans(4), Jan Kihlberg(4), Carrie L. Shaffer(4), K. Syam Krishnan(4), Nils Pemberton(3), Jörgen Ådén(3), Maria Hadjifrangiskou(3), Emma K. Andersson(3)