Hwee Cheng Tan

Duke-NUS Medical School — Singapore

Medicine · Health Sciences

30h-index3.2kcitations67works2.32yr avg
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Research Topics

Mosquito-borne diseases and control(51), Viral Infections and Vectors(33), Malaria Research and Control(16), HIV Research and Treatment(9), Viral Infections and Outbreaks Research(9)

Publications67 total

Reduced dengue virus pre-membrane protein-HMGB1 interaction activates host cell transcription to attenuate infection
npj Vaccines·2026Open Access
Comparison of human cerebral organoids infected with wild-type Zika versus attenuated DN-2 virus strains uncovers differences in host immune responses
Cell Communication and Signaling·2025Open Access
Integrated analysis of serum metabolomics and fecal microbiome in infants with necrotizing enterocolitis
Frontiers in Microbiology·2025· 1 citedOpen Access
Dengue virus 3’ untranslated region regulates RNA genome translation
2025· 1 citedOpen Access
A prM mutation that attenuates dengue virus replication in human cells enhances midgut infection in mosquitoes
Science Translational Medicine·2024· 9 cited
A natural human cell-adapted dengue type 3 virus strain
Microbiology Spectrum·2024· 1 citedOpen Access
Electron transport chain capacity expands yellow fever vaccine immunogenicity
EMBO Molecular Medicine·2024· 4 citedOpen Access
A phase I/II randomized, double-blinded, placebo-controlled trial of a self-amplifying Covid-19 mRNA vaccine
npj Vaccines·2022· 58 citedOpen Access
A fast-growing dengue virus mutant reveals a dual role of STING in response to infection
Open Biology·2022· 12 citedOpen Access
Author response for "A fast-growing dengue virus mutant reveals a dual role of STING in response to infection"
2022
A protocol to assess cellular bioenergetics in flavivirus-infected cells
STAR Protocols·2022· 5 citedOpen Access
Dysregulated metabolism underpins Zika-virus-infection-associated impairment in fetal development
Cell Reports·2021· 37 citedOpen Access
A mouse model of lethal respiratory dysfunction for SARS-CoV-2 infection
Antiviral Research·2021· 19 citedOpen Access
A phase 1/2 randomized, double-blinded, placebo controlled ascending dose trial to assess the safety, tolerability and immunogenicity of ARCT-021 in healthy adults
2021· 21 citedOpen Access
Attenuated dengue viruses are genetically more diverse than their respective wild-type parents
npj Vaccines·2021· 14 citedOpen Access
Cell strain-derived induced pluripotent stem cell as a genetically controlled approach to investigating aging mechanisms and viral pathogenesis
2021Open Access
A single dose of self-transcribing and replicating RNA-based SARS-CoV-2 vaccine produces protective adaptive immunity in mice
Molecular Therapy·2021· 174 citedOpen Access
Temporal dynamics of the host molecular responses underlying severe COVID-19 progression and disease resolution
EBioMedicine·2021· 30 citedOpen Access
Aviremic organ transplant dengue virus transmission – A case report
American Journal of Transplantation·2021· 18 citedOpen Access
Live vaccine infection burden elicits adaptive humoral and cellular immunity required to prevent Zika virus infection
EBioMedicine·2020· 12 citedOpen Access
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Frequent Co-authors

Eng Eong Ooi(46), Summer L. Zhang(19), Kuan Rong Chan(17), Esther S. Gan(16), Eugenia Z. Ong(14), Subhash G. Vasudevan(9), Jenny G. Low(7), Milly M. Choy(6), October M. Sessions(5), Ayesa Syenina(5), Swee Sen Kwek(5), Satoru Watanabe(5), Ruklanthi de Alwis(4), Shiwei Chen(4), Yan Shan Leong(4), Clement Yau(4), Shirin Kalimuddin(4), Pad Chivukula(4), Angeline Lim(4), Brendon J. Hanson(4)