Zsófia Hegedüs

University of Szeged — Hungary

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index683citations35works0.52yr avg
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Research Topics

Chemical Synthesis and Analysis(12), Protein Structure and Dynamics(5), RNA and protein synthesis mechanisms(5), Cancer, Hypoxia, and Metabolism(4), Monoclonal and Polyclonal Antibodies Research(4)

Publications35 total

Discordance between in silico and in vitro results on proteolytic stability of milk protein-derived DPP-4 inhibitory peptides
European Food Research and Technology·2025· 2 cited
Trastuzumab Decreases the Expression of G1/S Regulators and Syndecan-4 Proteoglycan in Human Rhabdomyosarcoma
International Journal of Molecular Sciences·2025Open Access
Selective allostery perturbation reveals the structural mechanism of the negative regulation for hypoxia inducible factor-1α
2024Open Access
Site-directed allostery perturbation to probe the negative regulation of hypoxia inducible factor-1α
RSC Chemical Biology·2024Open Access
Structural Adaptation of the Single-Stranded DNA-Binding Protein C-Terminal to DNA Metabolizing Partners Guides Inhibitor Design
Pharmaceutics·2023· 4 citedOpen Access
Structural adaptation of the single-stranded DNA-binding protein C-terminal to DNA metabolizing partners guides in-hibitor design
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Structural adaptation of the single-stranded DNA-binding protein C-terminal to DNA metabolizing partners guides in-hibitor design
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Improved Metal-Free Approach for the Synthesis of Protected Thiol Containing Thymidine Nucleoside Phosphoramidite and Its Application for the Synthesis of Ligatable Oligonucleotide Conjugates
Pharmaceutics·2023· 1 citedOpen Access
Author response for "Towards identification of protein-protein interaction stabilizers <i>via</i> inhibitory peptide-fragment hybrids using templated fragment ligation"
2022
Towards Identification of Protein-Protein Interaction Stabilizers via Inhibitory Peptide-Fragment Hybrids Using Templated Fragment Ligation
2022Open Access
Understanding p300-transcription factor interactions using sequence variation and hybridization
RSC Chemical Biology·2022· 11 citedOpen Access
Towards identification of protein–protein interaction stabilizers <i>via</i> inhibitory peptide-fragment hybrids using templated fragment ligation
RSC Chemical Biology·2022· 2 citedOpen Access
Understanding p300-transcription factor interactions using sequence variation and hybridization
2021Open Access
Identification of β-strand mediated protein–protein interaction inhibitors using ligand-directed fragment ligation
Chemical Science·2021· 18 citedOpen Access
Query-guided protein–protein interaction inhibitor discovery
Chemical Science·2021· 15 citedOpen Access
Tunable Magnetic Hyperthermia Properties of Pristine and Mildly Reduced Graphene Oxide/Magnetite Nanocomposite Dispersions
Nanomaterials·2020· 13 citedOpen Access
Crystal structure of SHANK1 PDZ in complex with a peptide-small molecule hybrid
2020
Stapled Peptides as HIF‐1α/p300 Inhibitors: Helicity Enhancement in the Bound State Increases Inhibitory Potency
Chemistry - A European Journal·2020· 16 citedOpen Access
DPP‐4 Cleaves α/β‐Peptide Bonds: Substrate Specificity and Half‐Lives
ChemBioChem·2020· 4 citedOpen Access
Predicting and Experimentally Validating Hot-Spot Residues at Protein–Protein Interfaces
ACS Chemical Biology·2019· 90 citedOpen Access
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Frequent Co-authors

Tamás A. Martinek(15), Andrew J. Wilson(14), Richard B. Sessions(9), Fruzsina Hóbor(8), Thomas A. Edwards(7), Gail J. Bartlett(6), Edit Wéber(6), Kristina Hetherington(5), Éva Monostori(5), Vencel L. Petrovicz(5), Anasztázia Hetényi(5), Amaurys Ávila Ibarra(4), Derek N. Woolfson(4), Éva Bartus(4), Gerda Szakonyi(4), Stuart L. Warriner(4), Som Dutt(3), Kirstin Spence(3), Adam Nelson(3), Éva Kriston-Pál(3)