Andrew S. Mendiola

Gladstone Institutes — United States

Neuroscience · Life Sciences

17h-index1.9kcitations38works29.02yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(22), Retinal Diseases and Treatments(11), Chemokine receptors and signaling(6), Atherosclerosis and Cardiovascular Diseases(6), Immune cells in cancer(5)

Publications37 total

Machine learning reveals prominent spontaneous behavioral changes and treatment efficacy in humanized and transgenic Alzheimer's disease models
Cell Reports·2024· 15 citedOpen Access
Pioneering discovery and therapeutics at the brain-vascular-immune interface
Cell·2024· 13 cited
Fibrin drives thromboinflammation and neuropathology in COVID-19
Nature·2024· 78 citedOpen Access
Fibrin promotes oxidative stress and neuronal loss in traumatic brain injury via innate immune activation
Journal of Neuroinflammation·2024· 39 citedOpen Access
Un-BAFFling gray matter pathology in multiple sclerosis
Science Immunology·2024
Defining blood-induced microglia functions in neurodegeneration through multiomic profiling
Nature Immunology·2023· 112 citedOpen Access
Pharmacological depletion of microglia alleviates neuronal and vascular damage in the diabetic CX3CR1-WT retina but not in CX3CR1-KO or hCX3CR1I249/M280-expressing retina
Frontiers in Immunology·2023· 18 citedOpen Access
Defective <scp>fractalkine‐CX3CR1</scp> signaling aggravates neuroinflammation and affects recovery from cuprizone‐induced demyelination
Journal of Neurochemistry·2022· 17 citedOpen Access
Fibrinogen Depletion Ameliorates Inflammation and Vision Loss in Mouse Models of Diabetes
The Journal of Immunology·2022
Defibrinogenation Ameliorates Retinal Microgliosis and Inflammation in A CX3CR1-Independent Manner
ASN NEURO·2022· 16 citedOpen Access
ApoE and immunity in Alzheimer’s disease and related tauopathies: Low-density lipoprotein receptor to the rescue
Neuron·2021· 7 citedOpen Access
Retinal Microglia Depletion as a Tool to Determine the role of Microglia-Mediated Inflammation in the Diabetic Retina
Investigative Ophthalmology & Visual Science·2021Open Access
Fibrinogen in Microglia-Mediated Inflammation in Diabetic Retinopathy
Investigative Ophthalmology & Visual Science·2021· 1 citedOpen Access
Microglial CX3CR1 <sup>I249/M280</sup> variant limits neurogenesis and remyelination in cuprizone-induced multiple sclerosis model
2021Open Access
BMP receptor blockade overcomes extrinsic inhibition of remyelination and restores neurovascular homeostasis
Brain·2021· 30 citedOpen Access
Blood Coagulation Factor Fibrinogen in Tumor Pathogenesis of Central Nervous System B-Cell Lymphoma
American Journal Of Pathology·2021· 9 citedOpen Access
Microglial Gi-dependent dynamics regulate brain network hyperexcitability
Nature Neuroscience·2020· 151 citedOpen Access
Author Correction: Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
Nature Immunology·2020· 2 cited
Transcriptional profiling and therapeutic targeting of oxidative stress in neuroinflammation
Nature Immunology·2020· 195 citedOpen Access
Extracellular vesicle fibrinogen induces encephalitogenic CD8+ T cells in a mouse model of multiple sclerosis
Proceedings of the National Academy of Sciences·2019· 57 citedOpen Access
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Frequent Co-authors

Astrid E. Cardona(18), Sandra M. Cardona(16), Katerina Akassoglou(15), Jae Kyu Ryu(12), Kaira A. Church(11), Zhaoqi Yan(10), Mark A. Petersen(8), Difernando Vanegas(8), Anke Meyer‐Franke(7), Pamela E. Rios Coronado(6), Alexander R. Pico(6), Reuben Thomas(6), Reshmi Tognatta(6), Richard M. Ransohoff(6), Sophia Bardehle(5), Mark H. Ellisman(5), Mario Merlini(5), Rosa Meza-Acevedo(5), Andrew Tsin(5), Victoria A. Rafalski(4)