Hwai Wen Chang

BioAtla (United States) — United States

Medicine · Health Sciences

9h-index817citations10works11.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(3), Virus-based gene therapy research(2), CAR-T cell therapy research(2), Viral Infectious Diseases and Gene Expression in Insects(2), Parkinson's Disease Mechanisms and Treatments(1)

Publications10 total

Preclinical development of ozuriftamab vedotin (BA3021), a novel ROR2-specific conditionally active biologic antibody–drug conjugate
mAbs·2025· 9 citedOpen Access
Preclinical development of mecbotamab vedotin (BA3011), a novel, AXL-specific conditional active biologic antibody–drug conjugate
Antibody Therapeutics·2025· 5 citedOpen Access
A novel conditional active biologic anti-EpCAM x anti-CD3 bispecific antibody with synergistic tumor selectivity for cancer immunotherapy
mAbs·2024· 19 citedOpen Access
Generating tumor-selective conditionally active biologic anti-CTLA4 antibodies via protein-associated chemical switches
Proceedings of the National Academy of Sciences·2021· 43 citedOpen Access
Y box-binding protein 1 induces resistance to oncogenic transformation by the phosphatidylinositol 3-kinase pathway
Proceedings of the National Academy of Sciences·2003· 68 citedOpen Access
α-Synuclein maps to a quantitative trait locus for alcohol preference and is differentially expressed in alcohol-preferring and -nonpreferring rats
Proceedings of the National Academy of Sciences·2003· 126 citedOpen Access
The Catalytic Subunit of Phosphoinositide 3-Kinase: Requirements for Oncogenicity
Journal of Biological Chemistry·2000· 87 citedOpen Access
A random walk in oncogene space: the quest for targets.
PubMed·1999· 10 cited
Oncogenic transformation induced by the Qin protein is correlated with transcriptional repression
Proceedings of the National Academy of Sciences·1997· 35 citedOpen Access
Transformation of Chicken Cells by the Gene Encoding the Catalytic Subunit of PI 3-Kinase
Science·1997· 415 cited

Frequent Co-authors

Peter K. Vogt(5), Gerhard Frey(4), Haizhen Liu(4), Charles Xing(4), William J. Boyle(4), Jay M. Short(4), Masahiro Aoki(3), Jason S. Iacovoni(2), Jing Wang(2), Jian Chen(2), David Fruman(1), Kurt R. Auger(1), Alfonso Bellacosa(1), Philip N. Tsichlis(1), Lewis C. Cantley(1), Thomas M. Roberts(1), Tiebing Liang(1), John C. H. Spence(1), Lixiang Liu(1), Wendy N. Strother(1)