Alfonso Lavorgna

Johns Hopkins University — United States

Immunology and Microbiology · Life Sciences

15h-index968citations23works9.02yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

T-cell and Retrovirus Studies(12), Vector-Borne Animal Diseases(11), Animal Disease Management and Epidemiology(9), NF-κB Signaling Pathways(6), interferon and immune responses(6)

Publications23 total

The tyrosine kinase KDR is essential for the survival of HTLV-1-infected T cells by stabilizing the Tax oncoprotein
Nature Communications·2024· 9 citedOpen Access
The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation
PLoS Pathogens·2020· 23 citedOpen Access
The E3/E4 ubiquitin conjugation factor UBE4B interacts with and ubiquitinates the HTLV-1 Tax oncoprotein to promote NF-κB activation
2020· 6 citedOpen Access
A critical role for IL-17RB signaling in HTLV-1 tax-induced NF-κB activation and T-cell transformation
Retrovirology·2015· 18 citedOpen Access
Aryl Hydrocarbon Receptor Interacting Protein Targets IRF7 to Suppress Antiviral Signaling and the Induction of Type I Interferon
Journal of Biological Chemistry·2015· 40 citedOpen Access
CIKS/DDX3X Interaction Controls the Stability of the <i>Zc3h12a</i> mRNA Induced by IL-17
The Journal of Immunology·2015· 35 citedOpen Access
Myocyte enhancer factor (MEF)-2 plays essential roles in T-cell transformation associated with HTLV-1 infection by stabilizing complex between Tax and CREB
Retrovirology·2015· 21 citedOpen Access
Oncogenic Human T-Cell Lymphotropic Virus Type 1 Tax Suppression of Primary Innate Immune Signaling Pathways
Journal of Virology·2015· 21 citedOpen Access
Regulation of HTLV-1 Tax Stability, Cellular Trafficking and NF-κB Activation by the Ubiquitin-Proteasome Pathway
Viruses·2014· 41 citedOpen Access
A Critical Role for IL-17RB Signaling in HTLV-1 Tax-Induced NF-κB Activation and T-Cell Transformation
PLoS Pathogens·2014· 47 citedOpen Access
Is there a Role for Ubiquitin or SUMO in Human T-Cell Leukemia Virus Type 2 Tax-Induced NF-κB Activation?
Future Virology·2013· 1 citedOpen Access
An RNA Interference Screen Identifies the Deubiquitinase STAMBPL1 as a Critical Regulator of Human T-Cell Leukemia Virus Type 1 Tax Nuclear Export and NF-κB Activation
Journal of Virology·2012· 1 citedOpen Access
EBV LMP1: New and shared pathways to NF-κB activation
Proceedings of the National Academy of Sciences·2012· 40 citedOpen Access
An RNA Interference Screen Identifies the Deubiquitinase STAMBPL1 as a Critical Regulator of Human T-Cell Leukemia Virus Type 1 Tax Nuclear Export and NF-κB Activation
Journal of Virology·2012· 43 citedOpen Access
STAMBPL1 is a deubiquitinating enzyme that regulates HTLV-I Tax subcellular localization and NF-kB activation
Retrovirology·2011· 5 citedOpen Access
NF-κB-dependent cytokine secretion controls Fas expression on chemotherapy-induced premature senescent tumor cells
Oncogene·2011· 69 cited
Protection against Pseudomonas aeruginosa lung infection in mice by recombinant OprF-pulsed dendritic cell immunization
BMC Microbiology·2010· 40 citedOpen Access
TNF receptor-associated factor 1 is a positive regulator of the NF-κB alternative pathway
Molecular Immunology·2009· 30 cited
NESCA: A new NEMO/IKKgamma and TRAF6 interacting protein
Journal of Cellular Physiology·2009· 8 citedOpen Access
A novel insertional mutation in the prion protein gene: clinical and bio-molecular findings
Journal of Neurology Neurosurgery & Psychiatry·2008· 13 cited
page 1 of 2Next →

Frequent Co-authors

Edward W. Harhaj(14), Antonio Leonardi(8), Silvestro Formisano(5), Francesco Pacifico(4), Suchitra Mohanty(3), Claudio Mauro(2), Alessio Iannetti(2), Renato Acquaviva(2), Elvira Crescenzi(2), Anna Maria Salzano(2), Andrea Scaloni(2), Masao Matsuoka(2), Teng Han(2), Young Bong Choi(2), Jiawen Zhang(2), Stefano Mellone(1), Pasquale Vito(1), Carlo Vascotto(1), Gianluca Tell(1), Emilia Vuttariello(1)