George K. Christophides

Imperial College London — United Kingdom

Medicine · Health Sciences

61h-index15.5kcitations204works3.92yr avg
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Research Topics

Mosquito-borne diseases and control(88), Invertebrate Immune Response Mechanisms(84), Insect symbiosis and bacterial influences(76), Malaria Research and Control(70), Insect Resistance and Genetics(36)

Publications204 total

Gene-drive-capable mosquitoes suppress patient-derived malaria in Tanzania
Nature·2025· 3 citedOpen Access
The nanosd integral gene drive enables population modification of the malaria vector <i>Anopheles gambiae</i>
G3 Genes Genomes Genetics·2025Open Access
Author Reply to Peer Reviews of The nanosd integral gene drive enables population modification of the malaria vector Anopheles gambiae
2025
Metabolic reprogramming and gut microbiota ecology drive divergent <i>Plasmodium vivax</i> infection outcomes in <i>Anopheles darlingi</i>
2025Open Access
De novo assembly of plasmodium interspersed repeat (pir) genes from Plasmodium vivax RNAseq data suggests geographic conservation of sub-family transcription
BMC Genomics·2025· 1 citedOpen Access
The nanos <sup>d</sup> integral gene drive enables population modification of the malaria vector <i>Anopheles gambiae</i>
2025Open Access
Nanobody-mediated targeting of Plasmodium falciparum PfPIMMS43 can block malaria transmission in mosquitoes
Communications Biology·2025Open Access
A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184
Nature Communications·2025· 10 citedOpen Access
De novo assembly of plasmodium interspersed repeat (pir) genes from Plasmodium vivax RNAseq data suggests geographic conservation of sub-family transcription
2025Open Access
Malaria vectors with leaky guts
Nature Microbiology·2025
VEClim: An early warning decision support system for climate-sensitive vector activity and vector-borne disease risk assessment
Wellcome Open Research·2024· 3 citedOpen Access
Essential vector-disease resource faces shutdown without funding
Nature·2024· 1 cited
Publisher Correction: Considerations for first field trials of low-threshold gene drive for malaria vector control
Malaria Journal·2024Open Access
Considerations for first field trials of low-threshold gene drive for malaria vector control
Malaria Journal·2024· 28 citedOpen Access
Immune interactions between mosquitoes and microbes during midgut colonization
Current Opinion in Insect Science·2024· 15 citedOpen Access
A chromosomal reference genome sequence for the malaria mosquito, Anopheles gambiae, Giles, 1902, Ifakara strain
Wellcome Open Research·2024· 2 citedOpen Access
REL2 overexpression in the <i>Anopheles gambiae</i> midgut causes major transcriptional changes but fails to induce an immune response
2024· 3 citedOpen Access
VEuPathDB: the eukaryotic pathogen, vector and host bioinformatics resource center in 2023
Nucleic Acids Research·2023· 217 citedOpen Access
Intracellular <i>Plasmodium</i> aquaporin 2 is important for sporozoite production in the mosquito vector and malaria transmission
Proceedings of the National Academy of Sciences·2023· 2 citedOpen Access
Identification of genes required for Plasmodium gametocyte-to-sporozoite development in the mosquito vector
Cell Host & Microbe·2023· 10 citedOpen Access
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Frequent Co-authors

Fotis C. Kafatos(22), Stephan Meister(8), Evgeny M. Zdobnov(8), Frank H. Collins(8), Robert M. MacCallum(7), George Dimopoulos(6), Mike A. Osta(6), Dina Vlachou(6), Christos Louis(6), Peter Arensburger(5), Pantelis Topalis(5), Carolina Barillas‐Mury(5), Kristin Michel(5), Mara Lawniczak(5), Michael Povelones(5), Mathilde Gendrin(5), Peter W. Atkinson(4), Claudia Blass(4), Anastasios C. Koutsos(4), Ewan Birney(4)