Jon N. Rumbley

Biochemistry, Genetics and Molecular Biology · Life Sciences

23h-index2.2kcitations50works2.62yr avg
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Research Topics

Photosynthetic Processes and Mechanisms(17), Protein Structure and Dynamics(12), Hemoglobin structure and function(9), Enzyme Structure and Function(7), Mitochondrial Function and Pathology(6)

Publications50 total

Development of novel mitochondrial pyruvate carrier inhibitors for breast cancer treatment
Journal of Biological Chemistry·2025· 1 citedOpen Access
Exploring the impact of mitochondrial-targeting anthelmintic agents with GLUT1 inhibitor BAY-876 on breast cancer cell metabolism
BMC Cancer·2024· 8 citedOpen Access
Development of fluoro-7-aminocarboxycoumarin-based mitochondrial pyruvate carrier inhibitors as anticancer agents
2024· 1 citedOpen Access
Repurposing mitochondrial-targeting anthelmintic agents with GLUT1 inhibitor BAY-876 for cancer therapy
2024· 1 citedOpen Access
Synthesis and Biological Evaluation of Telmisartan Alkylamine Derivatives as Potential Anticancer Agents
Anticancer Research·2024· 2 citedOpen Access
Synthesis and biological evaluation of benzofuran piperazine derivatives as potential anticancer agents
Bioorganic & Medicinal Chemistry Letters·2023· 21 cited
Synthesis and biological evaluation of N, N-dialkylcarboxy coumarin-NO donor conjugates as potential anticancer agents
Bioorganic & Medicinal Chemistry Letters·2021· 16 cited
Synthesis and biological evaluation of a novel anticancer agent CBISC that induces DNA damage response and diminishes levels of mutant-p53
Biochemical and Biophysical Research Communications·2021· 1 cited
Synthesis and biological evaluation of novel 2-alkoxycarbonylallylester phosphonium derivatives as potential anticancer agents
Bioorganic & Medicinal Chemistry Letters·2021· 8 cited
A Global Analysis of Enzyme Compartmentalization to Glycosomes
Pathogens·2020· 12 citedOpen Access
Development of Novel Silyl Cyanocinnamic Acid Derivatives as Metabolic Plasticity Inhibitors for Cancer Treatment
Scientific Reports·2019· 20 citedOpen Access
Novel N,N-dialkyl cyanocinnamic acids as monocarboxylate transporter 1 and 4 inhibitors
Oncotarget·2019· 34 citedOpen Access
The <i>Caenorhabditis elegans spe‐49</i> gene is required for fertilization and encodes a sperm‐specific transmembrane protein homologous to SPE‐42
Molecular Reproduction and Development·2018· 25 cited
Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase
Journal of Human Genetics·2013· 6 citedOpen Access
Thyroid Hormone Analog and ENDO- and Xenobiotic Substrate Preference of High-Affinity Thyroxine Transporter OATP1C1
2011
Fertilization in C. elegans requires an intact C-terminal RING finger in sperm protein SPE-42
BMC Developmental Biology·2011· 19 citedOpen Access
Evidence of Evolutionary Conservation of Function between the Thyroxine Transporter Oatp1c1 and Major Facilitator Superfamily Members
Endocrinology·2010· 19 citedOpen Access
The Blood-Brain Barrier Thyroxine Transporter Organic Anion-Transporting Polypeptide 1c1 Displays Atypical Transport Kinetics
Endocrinology·2009· 46 citedOpen Access
Design and Evaluation of New Analogs of the Sweet Protein Brazzein
Chemical Senses·2009· 25 citedOpen Access
Fast structural dynamics in reduced and oxidized cytochrome <i>c</i>
Protein Science·2009· 14 citedOpen Access
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Frequent Co-authors

S. Walter Englander(13), Robert B. Gennis(12), Venkatram R. Mereddy(11), Conor T. Ronayne(9), Tanner J. Schumacher(7), Peter R. Rich(6), Grant W. Anderson(5), A. John Moody(5), Zachary Gardner(5), Leland Mayne(4), Haripada Maity(4), Daniel E. Westholm(4), Shirisha Jonnalagadda(4), Sravan K. Jonnalagadda(4), Grady L. Nelson(4), Lucas N. Solano(4), Krishna M.G. Mallela(3), Linh Hoang(3), Lester R. Drewes(3), Jon Holy(3)