Denise L. Driscoll

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index584citations24works0.02yr avg
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Research Topics

Ubiquitin and proteasome pathways(15), Cell death mechanisms and regulation(12), Autophagy in Disease and Therapy(7), Synthesis and biological activity(3), Cancer-related Molecular Pathways(3)

Publications24 total

Supplementary Figure 8 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Figures 1-4 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Methods, Figure and Table Legends from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Figure 8 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Table 3A-F from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Methods, Figure and Table Legends from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Figures 5-7 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Figures 1-4 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Figures 5-7 from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Data from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Supplementary Table 3A-F from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Data from Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
2023Open Access
Plk1 Inhibition Causes Post-Mitotic DNA Damage and Senescence in a Range of Human Tumor Cell Lines
PLoS ONE·2014· 59 citedOpen Access
A Fully Synthetic and Biochemically Validated Phosphatidyl Inositol-3-Phosphate Hapten via Asymmetric Synthesis and Native Chemical Ligation
Journal of the American Chemical Society·2013· 14 citedOpen Access
MLN0905, a Small-Molecule <i>PLK1</i> Inhibitor, Induces Antitumor Responses in Human Models of Diffuse Large B-cell Lymphoma
Molecular Cancer Therapeutics·2012· 21 cited
Discovery of a Potent and Orally Bioavailable Benzolactam-Derived Inhibitor of Polo-Like Kinase 1 (MLN0905)
Journal of Medicinal Chemistry·2011· 54 citedOpen Access
Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib
Cancer Research·2010· 103 citedOpen Access
Abstract A70: A genome-wide siRNA screen for modulators of cell death induced by the proteasome inhibitor bortezomib
Molecular Cancer Therapeutics·2009· 1 cited
Soluble 2-Substituted Aminopyrido[2,3-<i>d</i>]pyrimidin-7-yl Ureas. Structure−Activity Relationships against Selected Tyrosine Kinases and Exploration of in Vitro and in Vivo Anticancer Activity
Journal of Medicinal Chemistry·2001· 53 citedOpen Access
3-(3,5-Dimethoxyphenyl)-1,6-naphthyridine-2,7-diamines and Related 2-Urea Derivatives Are Potent and Selective Inhibitors of the FGF Receptor-1 Tyrosine Kinase
Journal of Medicinal Chemistry·2000· 46 citedOpen Access
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Frequent Co-authors

Anne L. Burkhardt(15), Siquan Chen(14), Jonathan L. Blank(14), Theodore Peters(14), David M. Rappoli(14), Michael D. Pickard(14), Saurabh Menon(14), Trupti Lingaraj(14), Khristofer Garcia(14), Darshan S. Sappal(14), Jesse Gray(14), Paul Hales(14), Patrick Leroy(14), John Ringeling(14), Claudia Rabino(14), James J. Spelman(14), Jay P. Morgenstern(14), Eric S. Lightcap(14), Xiaozhen J. Liu(13), Wei Chen(12)