Ghanashyam D. Ghadge

University of Chicago — United States

Medicine · Health Sciences

27h-index2.4kcitations58works0.02yr avg
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Research Topics

Amyotrophic Lateral Sclerosis Research(18), Neurogenetic and Muscular Disorders Research(13), RNA Research and Splicing(10), Virus-based gene therapy research(10), Viral Infections and Immunology Research(10)

Publications58 total

Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers
International Journal of Molecular Sciences·2022· 17 citedOpen Access
Kozak Similarity Score Algorithm Identifies Alternative Translation Initiation Codons Implicated in Cancers
Preprints.org·2022· 1 citedOpen Access
Machine learning predicts translation initiation sites in neurologic diseases with nucleotide repeat expansions
PLoS ONE·2022· 50 citedOpen Access
A C. elegans model of C9orf72-associated ALS/FTD uncovers a conserved role for eIF2D in RAN translation
Nature Communications·2021· 49 citedOpen Access
Machine learning predicts translation initiation sites in neurologic diseases with expanded repeats
2021· 1 citedOpen Access
RNA-Binding Protein Altered Expression and Mislocalization in Multiple Sclerosis (4200)
Neurology·2020
RNA-binding protein altered expression and mislocalization in MS
Neurology Neuroimmunology & Neuroinflammation·2020· 28 citedOpen Access
Knockdown of GADD34 in neonatal mutant SOD1 mice ameliorates ALS
Neurobiology of Disease·2019· 23 citedOpen Access
RNA-binding protein altered expression and mislocalization in multiple sclerosis
2019Open Access
TDP-43 PROTEINOPATHY IN THE PATHOGENESIS OF THEILER'S MURINE ENCEPHALOMYELITIS VIRUS INDUCED DISEASES
2019
TDP-43 proteinopathy in Theiler’s murine encephalomyelitis virus infection
PLoS Pathogens·2019· 28 citedOpen Access
Single chain variable fragment antibodies directed against SOD1 ameliorate disease in mutant SOD1 transgenic mice
Neurobiology of Disease·2018· 33 citedOpen Access
Translation of dipeptide repeat proteins from the C9ORF72 expanded repeat is associated with cellular stress
Neurobiology of Disease·2018· 119 citedOpen Access
Poloxamer 188 decreases membrane toxicity of mutant SOD1 and ameliorates pathology observed in SOD1 mouse model for ALS
Neurobiology of Disease·2018· 12 citedOpen Access
S-acylation of SOD1, CCS, and a stable SOD1-CCS heterodimer in human spinal cords from ALS and non-ALS subjects
Scientific Reports·2017· 18 citedOpen Access
Involvement of cardiovirus leader in host cell-restricted
2016
Palmitoylation of Superoxide Dismutase 1 (SOD1) Is Increased for Familial Amyotrophic Lateral Sclerosis-linked SOD1 Mutants
Journal of Biological Chemistry·2013· 46 citedOpen Access
Corrigendum to “Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1” [Neurobiol. Dis. 56 (2013) 74–78]
Neurobiology of Disease·2013· 2 citedOpen Access
Single chain variable fragment antibodies block aggregation and toxicity induced by familial ALS-linked mutant forms of SOD1
Neurobiology of Disease·2013· 15 citedOpen Access
Mutant SOD1 forms ion channel: Implications for ALS pathophysiology
Neurobiology of Disease·2011· 26 citedOpen Access
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Frequent Co-authors

Raymond P. Roos(35), Yoshifumi Sonobe(8), Joaquı́n Jordán(6), James A. Radosevich(6), Bayar Thimmapaya(5), Vytautas P. Bindokas(4), Jochen H.M. Prehn(4), Richard J. Miller(4), Marı́a F. Galindo(3), Jeffrey M. Leiden(3), Amos Bodner(3), Katsuhisa Masaki(3), Pawan Malhotra(3), Alec C. Gleason(3), Lijun Wang(3), Brian K. Kay(3), G. Kenneth Haines(3), B. Thimmappaya(3), G. Kenneth Haines(3), J. P. Lee(2)