Maureen Pickarski

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Medicine · Health Sciences

17h-index3.1kcitations26works0.02yr avg
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Research Topics

Bone health and treatments(20), Bone Metabolism and Diseases(16), Bone health and osteoporosis research(8), Osteoarthritis Treatment and Mechanisms(6), Bone and Joint Diseases(5)

Publications26 total

Effects of odanacatib on bone-turnover markers in osteoporotic postmenopausal women: a post hoc analysis of the LOFT study
Osteoporosis International·2022· 2 cited
Effects of long term treatment with high doses of odanacatib on bone mass, bone strength, and remodeling/modeling in newly ovariectomized monkeys
Bone·2016· 19 cited
Effects of odanacatib on bone matrix mineralization in rhesus monkeys are similar to those of alendronate
Bone Reports·2016· 3 citedOpen Access
Effects of Long-Term Odanacatib Treatment on Bone Gene Expression in Ovariectomized Adult Rhesus Monkeys: Differentiation From Alendronate
Journal of Bone and Mineral Research·2015· 12 citedOpen Access
Orally active αvβ3 integrin inhibitor MK-0429 reduces melanoma metastasis
Oncology Reports·2015· 52 citedOpen Access
PDGF-BB secreted by preosteoclasts induces angiogenesis during coupling with osteogenesis
Nature Medicine·2014· 912 citedOpen Access
Efficacy of a Cathepsin K Inhibitor in a Preclinical Model for Prevention and Treatment of Breast Cancer Bone Metastasis
Molecular Cancer Therapeutics·2014· 85 cited
Comparing the disease modifying effects of alendronate to risedronate in the rat anterior cruciate ligament transection model of osteoarthritis
Osteoarthritis and Cartilage·2014· 1 cited
Altered Hematopoietic Stem Cell and Osteoclast Precursor Frequency in Cathepsin K Null Mice
Journal of Cellular Biochemistry·2014· 18 cited
Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: A head-to-head comparison with alendronate
Bone·2013· 37 cited
Differential effects of odanacatib and alendronate on bone turnover in the femoral neck of adult ovariectomized rhesus monkeys
Bone·2012· 3 cited
Effects of odanacatib compared to alendronate on bone remodeling and biomechanical properties of the lumbar spine in estrogen-deficient rhesus monkeys
Bone·2012
Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis
Bone·2012· 124 cited
Evaluation of high-resolution peripheral quantitative computed tomography, finite element analysis and biomechanical testing in a pre-clinical model of osteoporosis: A study with odanacatib treatment in the ovariectomized adult rhesus monkey
Bone·2012· 29 cited
Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey
Journal of Bone and Mineral Research·2011· 137 cited
Odanacatib reduces bone turnover and increases bone mass in the lumbar spine of skeletally mature ovariectomized rhesus monkeys
Journal of Bone and Mineral Research·2011· 116 cited
Molecular changes in articular cartilage and subchondral bone in the rat anterior cruciate ligament transection and meniscectomized models of osteoarthritis
BMC Musculoskeletal Disorders·2011· 85 citedOpen Access
The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking
Bone·2011· 105 cited
Differential effects of odanacatib compared to alendronate on bone turnover in adult ovariectomized rhesus monkeys
Bone·2011
Dual In Vivo Quantification of Integrin-targeted and Protease-activated Agents in Cancer Using Fluorescence Molecular Tomography (FMT)
Molecular Imaging and Biology·2009· 79 cited
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Frequent Co-authors

Le T. Duong(22), Gregg Wesolowski(10), Ya Zhuo(7), Brenda L Pennypacker(6), Tadashi Hayami(5), T. Cusick(4), Boyd B. Scott(4), Gideon A. Rodan(3), Kevin R. Scott(3), Richard Hargreaves(3), John Szumiloski(3), Rana Samadfam(3), L.T. Duong⁎(3), Donald B. Kimmel(2), P. Masarachia(2), Patrick P.S. Leung(2), Renata M. Oballa(2), Alexa Gleason(2), Bohumil Bednář(2), Donald S. Williams(2)