Kathy O'Briant

Fred Hutch Cancer Center — United States

Medicine · Health Sciences

25h-index10.1kcitations41works0.02yr avg
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Research Topics

Monoclonal and Polyclonal Antibodies Research(10), Toxin Mechanisms and Immunotoxins(9), Ovarian cancer diagnosis and treatment(8), HER2/EGFR in Cancer Research(7), Cancer-related molecular mechanisms research(5)

Publications41 total

Digital Genomic Quantification of Tumor-Infiltrating Lymphocytes
Science Translational Medicine·2013· 59 citedOpen Access
Evaluating the prognostic significance of <i>JAK2</i> in distant breast cancer recurrence.
Journal of Clinical Oncology·2013
Longitudinal Screening Algorithm That Incorporates Change Over Time in CA125 Levels Identifies Ovarian Cancer Earlier Than a Single-Threshold Rule
Journal of Clinical Oncology·2012· 75 citedOpen Access
Potential Role of HE4 in Multimodal Screening for Epithelial Ovarian Cancer
JNCI Journal of the National Cancer Institute·2011· 53 citedOpen Access
An integrative genomic approach identifies p73 and p63 as activators of miR-200 microRNA family transcription
Nucleic Acids Research·2011· 73 citedOpen Access
Activation of the MEK–S6 Pathway in High-grade Ovarian Cancers
Applied immunohistochemistry & molecular morphology·2010· 14 citedOpen Access
Integrative Proteomic Analysis of Serum and Peritoneal Fluids Helps Identify Proteins that Are Up-Regulated in Serum of Women with Ovarian Cancer
PLoS ONE·2010· 39 citedOpen Access
Assessing Lead Time of Selected Ovarian Cancer Biomarkers: A Nested Case–Control Study
JNCI Journal of the National Cancer Institute·2009· 199 citedOpen Access
Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: Evidence supporting a mesothelial-to-epithelial transition
Gynecologic Oncology·2009· 196 citedOpen Access
Repertoire of microRNAs in Epithelial Ovarian Cancer as Determined by Next Generation Sequencing of Small RNA cDNA Libraries
PLoS ONE·2009· 235 citedOpen Access
Circulating microRNAs as stable blood-based markers for cancer detection
Proceedings of the National Academy of Sciences·2008· 7.9k citedOpen Access
Proteomic Analysis of Ovarian Cancer Cells Reveals Dynamic Processes of Protein Secretion and Shedding of Extra-Cellular Domains
PLoS ONE·2008· 130 citedOpen Access
Bead-Based ELISA for Validation of Ovarian Cancer Early Detection Markers
Clinical Cancer Research·2006· 150 citedOpen Access
Serologic analysis of ovarian tumor antigens reveals a bias toward antigens encoded on 17q
International Journal of Cancer·2003· 86 cited
Evidence of a founder effect and refinement of the hereditary neuralgic amyotrophy (HNA) locus on 17q25 in American families
Human Genetics·2001· 24 cited
A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA→AAUGAA) leads to the IPEX syndrome
Immunogenetics·2001· 243 cited
Rater agreement and utility of the mutagen-induced chromosome damage assay.
PubMed·2001· 4 cited
Evidence for genetic heterogeneity in hereditary neuralgic amyotrophy
Neurology·2001· 33 cited
Synergistic interaction between anti-p185HER-2 ricin A chain immunotoxins and radionuclide conjugates for inhibiting growth of ovarian and breast cancer cells that overexpress HER-2.
PubMed·2000· 15 cited
SSA/RO52gene and expressed sequence tags in an 85 kb region of chromosome segment 11p15.5
International Journal of Cancer·2000· 6 citedOpen Access
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Frequent Co-authors

Robert C. Bast(13), Charles W. Drescher(12), Nicole Urban(11), Gerold Bepler(11), Muneesh Tewari(6), Beatrice S. Knudsen(5), Martin McIntosh(5), L. Daly(5), Rachael K. Parkin(4), Garnet L. Anderson(4), Jason D. Thorpe(4), Michèl Schummer(4), John T. Soper(4), C. Boyer(4), G Schreiber(4), K DeSombre(4), Andrew K. Godwin(3), Nathalie Scholler(3), Aviva P. Ventura(3), Andrew Berchuck(3)