Alexandre Pattyn

Inserm — France

Neuroscience · Life Sciences

27h-index5.3kcitations43works0.02yr avg
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Research Topics

Neurogenesis and neuroplasticity mechanisms(13), Developmental Biology and Gene Regulation(12), Axon Guidance and Neuronal Signaling(11), Pain Mechanisms and Treatments(9), Congenital heart defects research(6)

Publications43 total

Expression dynamics of functionally equivalent Neurog1/2 genes enable protracted neurogenesis and temporal emergence of somatosensory neuron lineages
Cell Reports·2026Open Access
Functional Equivalence of the Proneural Genes <i>Neurog1</i> and <i>Neurog2</i> in the Developing Dorsal Root Ganglia Highlights the Importance of Timing of Neurogenesis in Biasing Somatosensory Precursor Fates
2025Open Access
Expression Dynamics of Functionally Equivalent Neurog1/2 Genes Enable Protracted Neurogenesis and Temporal Emergence of Somatosensory Neuron Lineages
SSRN Electronic Journal·2025Open Access
FXYD2 antisense oligonucleotide provides an efficient approach for long-lasting relief of chronic peripheral pain
JCI Insight·2023· 4 citedOpen Access
Neurog2 Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability among Neural-Crest-Derived Somatosensory Progenitors
Cell Reports·2019· 19 citedOpen Access
A novel ASO based approach to treat peripheral neuropathic pain
SPIRE - Sciences Po Institutional REpository·2019
PRDM12 Is Required for Initiation of the Nociceptive Neuron Lineage during Neurogenesis
Cell Reports·2019· 52 citedOpen Access
&lt;i&gt;Neurog2&lt;/i&gt;-Deficiency Uncovers a Critical Period of Cell Fate Plasticity and Vulnerability Among Neural Crest-Derived Somatosensory Progenitors
SSRN Electronic Journal·2019· 1 citedOpen Access
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice
Nature Communications·2018· 60 citedOpen Access
Fxyd2 regulates Aδ- and C-fiber mechanosensitivity and is required for the maintenance of neuropathic pain
Scientific Reports·2016· 27 citedOpen Access
Onset of Spinal Cord Astrocyte Precursor Emigration from the Ventricular Zone Involves the Zeb1 Transcription Factor
Cell Reports·2016· 18 citedOpen Access
Zeb Family Members and Boundary Cap Cells Underlie Developmental Plasticity of Sensory Nociceptive Neurons
Developmental Cell·2015· 18 citedOpen Access
CaMKK-CaMK1a, a New Post-Traumatic Signalling Pathway Induced in Mouse Somatosensory Neurons
PLoS ONE·2014· 16 citedOpen Access
ISDN2012_0208: The spinal cord ependymal region: A stem cell niche in the caudal central nervous system
International Journal of Developmental Neuroscience·2012· 2 cited
The Transcription Factor c-Maf Controls Touch Receptor Development and Function
Science·2012· 175 cited
Regulation of the Na,K-ATPase Gamma-Subunit FXYD2 by Runx1 and Ret Signaling in Normal and Injured Non-Peptidergic Nociceptive Sensory Neurons
PLoS ONE·2012· 20 citedOpen Access
The transcription factor Cux2 marks development of an A-delta sublineage of TrkA sensory neurons
Developmental Biology·2011· 48 cited
OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution
Genome Research·2010· 229 citedOpen Access
Low-Threshold Mechanoreceptor Subtypes Selectively Express MafA and Are Specified by Ret Signaling
Neuron·2009· 107 citedOpen Access
Defective Respiratory Rhythmogenesis and Loss of Central Chemosensitivity in Phox2b Mutants Targeting Retrotrapezoid Nucleus Neurons
Journal of Neuroscience·2009· 136 citedOpen Access
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Frequent Co-authors

Jean‐François Brunet(16), Patrick Carroll(16), Christo Goridis(14), Stéphanie Ventéo(14), Jean Valmier(7), David Ohayon(5), Alain Garcès(5), Cyril Rivat(5), Simon Desiderio(5), Pauline Cabochette(5), Steeve Bourane(4), Ilana Méchaly(4), Stéphane Dauger(3), Jorge Gallego(3), Anna Vallstedt(3), Johan Ericson(3), Marie‐Rose Hirsch(3), Carmen Birchmeier(3), Véronique Dubreuil(3), Jean-Charles Sabourin(3)