Navin Varadarajan

University of Houston — United States

Medicine · Health Sciences

31h-index3.8kcitations201works8.02yr avg
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Research Topics

CAR-T cell therapy research(97), Immune Cell Function and Interaction(66), T-cell and B-cell Immunology(45), Immunotherapy and Immune Responses(30), Cancer Immunotherapy and Biomarkers(22)

Publications199 total

Reactivating mutant p53 in T cells enhances anti-tumor activity in Acute Myeloid Leukemia
Blood·2025
Figure S3 from TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength
2025Open Access
Figure S1 from TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength
2025Open Access
Figure S4 from TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength
2025Open Access
Figure S2 from TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength
2025Open Access
TIGIT Affects CAR NK-cell Effector Function in the Solid Tumor Microenvironment by Modulating Immune Synapse Strength
Cancer Immunology Research·2025· 1 citedOpen Access
Mucosal vaccines with STING-agonist liposomal formulations inhibit RSV (respiratory syncytial virus) replication in cotton rats
Vaccine·2025· 1 cited
Somatic TP53 Mutations Drive T and NK Cell Dysfunction in AML and Can be Rescued by Reactivating Wild Type p53
2025· 2 citedOpen Access
Mesoscopic p53-rich clusters represent a new class of protein condensates
Biophysics Reviews·2025
Author Correction: A microfluidic assay for the quantification of the metastatic propensity of breast cancer specimens
Nature Biomedical Engineering·2025Open Access
Molecular dynamics at immune synapse lipid rafts influence the cytolytic behavior of CAR T cells
Science Advances·2025· 12 citedOpen Access
Mucosal Vaccines with Sting-Agonist Liposomal Formulations Inhibit Rsv (Respiratory Syncytial Virus) Replication in Cotton Rats
SSRN Electronic Journal·2025Open Access
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Carolina Digital Repository (University of North Carolina at Chapel Hill)·2024· 6 citedOpen Access
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers
Nature·2024· 155 citedOpen Access
TP53 Mutations within T Cells Induce T-Cell Exhaustion and Functional Impairment in TP53 Mutant AML
Blood·2024· 1 cited
139 Single-cell proliferation assay enables rapid and quantitative donor screening
Regular and Young Investigator Award Abstracts·2024Open Access
1112 Sticky T cells: engineered T cells targeting biglycan on tumor endothelial cells enhance infiltration into metastatic tumors
Regular and Young Investigator Award Abstracts·2024Open Access
346 Reprogramming the tumor microenvironment: endowing T and NK cells with the ability to degrade the extracellular matrix
Regular and Young Investigator Award Abstracts·2024Open Access
1088 Single-cell functional analysis accelerates design, translational research, clinical development, and process development of immunotherapies
Regular and Young Investigator Award Abstracts·2024Open Access
Data from CD28 Costimulation Augments CAR Signaling in NK Cells via the LCK/CD3ζ/ZAP70 Signaling Axis
2024Open Access
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Frequent Co-authors

Melisa Martinez-Paniagua(11), Gabrielle Romain(11), George Georgiou(10), Ali Rezvan(10), Mohsen Fathi(9), Ivan Liadi(9), Xingyue An(8), Jay R T. Adolacion(7), Laurence J.N. Cooper(7), Brent L. Iverson(6), Harjeet Singh(6), Badrinath Roysam(6), Arash Saeedi(6), Irfan Bandey(5), Ken Chen(4), Ankit Mahendra(4), Jason Roszik(4), May Daher(3), Rafet Başar(3), Nadima Uprety(3)