Lisa Nagase

High Energy Accelerator Research Organization — Japan

Medicine · Health Sciences

7h-index452citations17works2.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Helicobacter pylori-related gastroenterology studies(10), Galectins and Cancer Biology(7), Protein Tyrosine Phosphatases(5), Cellular transport and secretion(3), Protein Kinase Regulation and GTPase Signaling(2)

Publications17 total

<scp>PI</scp> 5 <scp>P</scp> 4 <scp>K</scp> inhibitors: promising opportunities and challenges
FEBS Journal·2025· 2 citedOpen Access
バクテリアのLysR型転写調節因子を含む転写活性化複合体の立体構造解明への挑戦
KAGAKU TO SEIBUTSU·2023Open Access
Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein
Scientific Reports·2023· 10 citedOpen Access
Anti-nanodisc antibodies specifically capture nanodiscs and facilitate molecular interaction kinetics studies for membrane protein
Research Square (Research Square)·2023Open Access
The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity
Structure·2022· 8 citedOpen Access
Activity-specificity trade-off gives PI5P4Kβ a nucleotide preference to function as a GTP-sensing kinase
2020Open Access
Differential Mechanisms for SHP2 Binding and Activation Are Exploited by Geographically Distinct Helicobacter pylori CagA Oncoproteins
Cell Reports·2017· 100 citedOpen Access
Deregulation mechanism of SHP2 by CagA from <i>Helicobacter pylori</i>
Acta Crystallographica Section A Foundations and Advances·2017Open Access
The H. pylori CagA protein with multiple EPIYA-C segment is a distinct risk factor for gastric carcinogenesis
The Molecular Biology Society of Japan·2016
Solution structure analysis of SHP2 in complex with the EPIYA region of Helicobacter pylori CagA
The Molecular Biology Society of Japan·2016
Host SHP1 phosphatase antagonizes Helicobacter pylori CagA and can be downregulated by Epstein–Barr virus
Nature Microbiology·2016· 89 cited
Structural study of the intrinsically disordered C-terminal region of Helicobacter pylori CagA
The Japanese Biochemical Society/The Molecular Biology Society of Japan·2015
Dramatic increase in SHP2 binding activity of Helicobacter pylori Western CagA by EPIYA-C duplication: its implications in gastric carcinogenesis
Scientific Reports·2015· 48 citedOpen Access
Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA
Cell Host & Microbe·2012· 160 citedOpen Access
The Smallest Active Fragment of Microtubule-Associated Protein 4 and Its Interaction with Microtubules in Phosphate Buffer
Bioscience Biotechnology and Biochemistry·2012· 1 citedOpen Access
Crystal structure of the Helicobacter pylori CagA oncoprotein
2012· 1 cited
Potentiation of Helicobacter pylori CagA Protein Virulence through Homodimerization
Journal of Biological Chemistry·2011· 33 citedOpen Access

Frequent Co-authors

Toshiya Senda(11), Takeru Hayashi(9), Masanori Hatakeyama(9), Miki Senda(8), Nobuhiro Suzuki(4), Koh Takeuchi(3), Yoshiki Ikeda(3), Atsuo T. Sasaki(3), Hiroko Morohashi(2), Hideaki Higashi(2), M. Horio(2), Yui Kashiba(2), D. Sasaya(2), Nagarajan Venugopalan(2), Hiroyuki Kumeta(2), Nobuo N. Noda(2), Fuyuhiko Inagaki(2), Naoko Murata‐Kamiya(2), Fuhito Nakagawa(2), Marin Kikkawa(2)