Geor Bakker

Scientific Consulting Group — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

17h-index1.5kcitations51works1.82yr avg
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Research Topics

Receptor Mechanisms and Signaling(15), Neuroscience and Neuropharmacology Research(13), Congenital heart defects research(12), Functional Brain Connectivity Studies(10), Congenital Heart Disease Studies(6)

Publications48 total

Social dysfunction relates to altered default mode network functional integrity across neuropsychiatric disorders: A replication and generalization study
2025· 1 citedOpen Access
Social dysfunction and facial emotion neural processing among neuropsychiatric disorders: a transdiagnostic study
Neuroscience Applied·2024Open Access
Social dysfunction is associated with altered facial emotion neural processing across diverse neuropsychiatric disorders
Neuroscience Applied·2024Open Access
Social Dysfunction and Neural Processing of Emotional Valence Across Depressive and Anxiety Disorders
Depression and Anxiety·2024· 4 citedOpen Access
Source‐based morphometry reveals structural brain pattern abnormalities in 22q11.2 deletion syndrome
Human Brain Mapping·2024· 6 citedOpen Access
Serial intravenous ketamine in treatment resistant depression produces reductions in symptoms and cerebral perfusion in reward and emotion-related brain regions
Neuroscience Applied·2024Open Access
A growing understanding of the role of muscarinic receptors in the molecular pathology and treatment of schizophrenia
Frontiers in Cellular Neuroscience·2023· 34 citedOpen Access
Targeting the Type 5 Metabotropic Glutamate Receptor: A Potential Therapeutic Strategy for Neurodegenerative Diseases?
Frontiers in Pharmacology·2022· 31 citedOpen Access
Effect of HTL0045725, a selective agonist of the orphan receptor GPR52, on kinase and transcription factor phosphorylation in striatal neurons
Neuroscience Applied·2022· 2 citedOpen Access
A phase 1b/2a multicenter study of the safety and preliminary pharmacodynamic effects of selective muscarinic M <sub>1</sub> receptor agonist HTL0018318 in patients with mild‐to‐moderate Alzheimer's disease
Alzheimer s & Dementia Translational Research & Clinical Interventions·2022· 7 citedOpen Access
Spatial Covariance of Cholinergic Muscarinic <scp>M<sub>1</sub></scp>/<scp>M<sub>4</sub></scp> Receptors in Parkinson's Disease
Movement Disorders·2021· 13 citedOpen Access
Effects of copy number variations on brain structure and risk for psychiatric illness: Large‐scale studies from the<scp>ENIGMA</scp>working groups on<scp>CNVs</scp>
Human Brain Mapping·2021· 67 citedOpen Access
Understanding Exposure-Receptor Occupancy Relationships for Metabotropic Glutamate Receptor 5 Negative Allosteric Modulators across a Range of Preclinical and Clinical Studies
Journal of Pharmacology and Experimental Therapeutics·2021· 7 citedOpen Access
Prioritizing Genetic Contributors to Cortical Alterations in 22q11.2 Deletion Syndrome Using Imaging Transcriptomics
Cerebral Cortex·2021· 13 citedOpen Access
Effects of copy number variations on brain structure and risk for psychiatric illness: Large-scale studies from the ENIGMA Working Groups on CNVs
2021· 12 citedOpen Access
Virtual Histology of Cortical Thickness and Shared Neurobiology in 6 Psychiatric Disorders
JAMA Psychiatry·2020· 247 citedOpen Access
Increased power by harmonizing structural MRI site differences with the ComBat batch adjustment method in ENIGMA
NeuroImage·2020· 257 citedOpen Access
MATLAB doesn't love me: an essay
2020· 1 citedOpen Access
Mapping Subcortical Brain Alterations in 22q11.2 Deletion Syndrome: Effects of Deletion Size and Convergence With Idiopathic Neuropsychiatric Illness
American Journal of Psychiatry·2020· 84 citedOpen Access
Lessons learned from using fMRI in the early clinical development of a mu-opioid receptor antagonist for disorders of compulsive consumption
Psychopharmacology·2020· 6 cited
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Frequent Co-authors

Thérèse van Amelsvoort(28), Oswald Bloemen(20), Jan Booij(18), Matthan W.A. Caan(15), Claudia Vingerhoets(12), Paul M. Thompson(9), Raquel E. Gur(9), Christopher R. K. Ching(9), Leila Kushan(9), Ariana Vajdi(9), J. Eric Schmitt(9), Donna M. McDonald‐McGinn(9), Beverly S. Emanuel(9), Celso Arango(8), Daqiang Sun(8), Michael Craig(8), David R. Roalf(8), Joanne Doherty(8), Adam Cunningham(8), Marianne van den Bree(8)