Irina Culminskaya

Social Science Research Council — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index1.3kcitations66works1.52yr avg
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Research Topics

Genetic Associations and Epidemiology(38), Genetics, Aging, and Longevity in Model Organisms(17), Bioinformatics and Genomic Networks(13), Birth, Development, and Health(12), Alzheimer's disease research and treatments(11)

Publications66 total

Pleiotropic Associations with Alzheimer’s Disease and Physical Activity: Sex Differences and the Effects of Environment
International Journal of Molecular Sciences·2024· 1 citedOpen Access
<i>TOMM40</i> and <i>APOC1</i> variants differentiate the impacts of the <i>APOE ε</i>4 allele on Alzheimer's disease risk across sexes, ages, and ancestries
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·2024· 2 citedOpen Access
Exome-Wide Association Study Identified Clusters of Pleiotropic Genetic Associations with Alzheimer’s Disease and Thirteen Cardiovascular Traits
Genes·2023· 5 citedOpen Access
Prevailing Antagonistic Risks in Pleiotropic Associations with Alzheimer’s Disease and Diabetes
Journal of Alzheimer s Disease·2023· 1 citedOpen Access
Associations of the APOE ε2 and ε4 alleles and polygenic profiles comprising APOE-TOMM40-APOC1 variants with Alzheimer’s disease biomarkers
Aging·2022· 16 citedOpen Access
<scp><i>APOE</i></scp> ɛ4 allele and <scp><i>TOMM40</i>‐<i>APOC1</i></scp> variants jointly contribute to survival to older ages
Aging Cell·2022· 15 citedOpen Access
EXOME-WIDE STUDY IDENTIFIED 12 PLEIOTROPIC LOCI ASSOCIATED WITH ALZHEIMER’S AND CARDIOVASCULAR DISEASE RISKS
Innovation in Aging·2022· 1 citedOpen Access
Inter- and intra-chromosomal modulators of the APOE ɛ2 and ɛ4 effects on the Alzheimer’s disease risk
GeroScience·2022· 10 citedOpen Access
Inter- and intra-chromosomal modulators of the <i>APOE</i> ε2 and ε4 effects on the Alzheimer’s disease risk
2022Open Access
Pleiotropy of Alzheimer’s Disease and Educational Attainment: Insights from the Summary Statistics
Innovation in Aging·2021Open Access
Pleiotropic predisposition to Alzheimer’s disease and educational attainment: insights from the summary statistics analysis
GeroScience·2021· 21 citedOpen Access
Definitive roles of TOMM40-APOE-APOC1 variants in the Alzheimer's risk
Neurobiology of Aging·2021· 42 citedOpen Access
Protective association of the ε2/ε3 heterozygote with Alzheimer's disease is strengthened by <i>TOMM40–APOE</i> variants in men
Alzheimer s & Dementia·2021· 13 citedOpen Access
Polygenic risk scores: pleiotropy and the effect of environment
GeroScience·2020· 6 citedOpen Access
Genetic and regulatory architecture of Alzheimer's disease in the <i>APOE</i> region
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·2020· 32 citedOpen Access
Haplotype architecture of the Alzheimer's risk in the <i>APOE</i> region via co‐skewness
Alzheimer s & Dementia Diagnosis Assessment & Disease Monitoring·2020· 20 citedOpen Access
APOE region molecular signatures of Alzheimer's disease across races/ethnicities
Neurobiology of Aging·2019· 33 citedOpen Access
Polygenic risk score for disability and insights into disability-related molecular mechanisms
GeroScience·2019· 2 citedOpen Access
GENOME-WIDE META-ANALYSIS SUPPORTS HETEROGENEITY IN POLYGENIC ARCHITECTURE OF DISABILITY
Innovation in Aging·2019Open Access
Quantitative and Qualitative Role of Antagonistic Heterogeneity in Genetics of Blood Lipids
The Journals of Gerontology Series A·2019· 12 citedOpen Access
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Frequent Co-authors

Alexander M. Kulminski(50), Konstantin G. Arbeev(37), Svetlana Ukraintseva(34), Anatoliy I. Yashin(21), Liubov Arbeeva(20), Yury Loika(19), Anatoli I. Yashin(16), Igor Akushevich(15), Deqing Wu(14), Eric Stallard(13), Liang He(8), Kenneth C. Land(7), Olivia Bagley(7), Ian Philipp(6), Elena Loiko(6), Matt Duan(5), Lucy Akushevich(5), Kaare Christensen(5), Alireza Nazarian(5), Mikhail Kovtun(4)