Esw Ngan

University of Hong Kong — Hong Kong

Medicine · Health Sciences

35h-index3.4kcitations157works0.52yr avg
OpenAlex↗ORCID↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Congenital gastrointestinal and neural anomalies(74), Intestinal Malrotation and Obstruction Disorders(28), Congenital Anomalies and Fetal Surgery(18), Neuroblastoma Research and Treatments(17), Digestive system and related health(16)

Publications157 total

Vinculin influences essential processes in enteric nervous system development and Hirschsprung disease pathogenesis
Journal of Clinical Investigation·2025Open Access
Vinculin mediates a dynamic signal flow underlying cardiac outflow tract development as revealed by single-cell and spatial transcriptomic analysis
Journal of Advanced Research·2025· 1 citedOpen Access
Organoid models of breathing disorders reveal patterning defect of hindbrain neurons caused by PHOX2B-PARMs
Stem Cell Reports·2023· 11 citedOpen Access
Transcriptomics of Hirschsprung disease patient-derived enteric neural crest cells reveals a role for oxidative phosphorylation
Nature Communications·2023· 20 citedOpen Access
Whole genome sequencing reveals epistasis effects within RET for Hirschsprung disease
Scientific Reports·2022· 2 citedOpen Access
Human Pluripotent Stem Cell-Based Models for Hirschsprung Disease: From 2-D Cell to 3-D Organoid Model
Cells·2022· 10 citedOpen Access
Depletion of hypercapnia-responsive neurons in human cerebral- and brainstem-organoids of congenital central hypoventilation syndrome
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
Depletion of hypercapnia-responsive neurons in human cerebral- and brainstem-organoids of congenital central hypoventilation syndrome
2022Open Access
Hedgehog-induced-oxidative-phosphorylation rescues neuronal differentiation defect of human enteric neural crest cells underlying Hirschsprung disease
2022Open Access
BACE2 variant identified from HSCR patient causes AD-like phenotypes in hPSC-derived brain organoids
Cell Death Discovery·2022· 27 citedOpen Access
New insights empowered by single-cell sequencing: From neural crest to enteric nervous system
Computational and Structural Biotechnology Journal·2022· 10 citedOpen Access
Ciliary protein Kif7 regulates Gli and Ezh2 for initiating the neuronal differentiation of enteric neural crest cells during development
Science Advances·2021· 15 citedOpen Access
Lineage tracing and single-cell analysis reveal proliferative Prom1+ tumour-propagating cells and their dynamic cellular transition during liver cancer progression
Gut·2021· 58 cited
Whole-genome analysis of noncoding genetic variations identifies multiscale regulatory element perturbations associated with Hirschsprung disease
Genome Research·2020· 15 citedOpen Access
Whole-genome analysis of noncoding genetic variations identifies multigranular regulatory element perturbations associated with Hirschsprung disease
2020Open Access
Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma
Developmental Cell·2020· 7 citedOpen Access
Activation of Hedgehog Signaling Promotes Development of Mouse and Human Enteric Neural Crest Cells, Based on Single-Cell Transcriptome Analyses
Gastroenterology·2019· 43 citedOpen Access
Functional study of non-coding variants in Hirschsprung disease using human pluripotent stem cell-based model
2019
Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma
Developmental Cell·2018· 55 cited
Identification of Genes Associated With Hirschsprung Disease, Based on Whole-Genome Sequence Analysis, and Potential Effects on Enteric Nervous System Development
Gastroenterology·2018· 80 cited
page 1 of 8Next →

Frequent Co-authors

Xiaoping Miao(15), Stacey S. Cherny(14), Man‐Ting So(13), María-Mercé García-Barceló(12), Clara Sze-Man Tang(12), Pak C. Sham(12), Paul Kwong‐Hang Tam(12), Vincent Chi‐Hang Lui(11), Kenneth Kak‐Yuen Wong(11), Bhy Chung(10), Xuelai Liu(7), Thomas Yuk-Yu Leon(6), Zhenwei Yuan(6), Sophia Y. Tsai(6), Paul Tam(6), Guo Cheng(6), Vincent Chi Hang Lui(6), Yan Chen(5), MH Sham(5), Maria‐Mercè Garcia‐Barceló(5)