Guihua Sun

City Of Hope National Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

25h-index3.7kcitations47works5.02yr avg
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Research Topics

MicroRNA in disease regulation(19), RNA Interference and Gene Delivery(14), RNA Research and Splicing(8), RNA modifications and cancer(6), Circular RNAs in diseases(6)

Publications47 total

Human iPSC-derived neural progenitor cells rescue motor function and brain pathology in symptomatic Canavan disease mice
Stem Cell Reports·2026Open Access
Multi-omics analysis of long-term cultured human islets
2024Open Access
Developing enhanced immunotherapy using NKG2A knockout human pluripotent stem cell-derived NK cells
Cell Reports·2024· 15 citedOpen Access
The Apolipoprotein E neutralizing antibody inhibits SARS‐CoV‐2 infection by blocking cellular entry of lipoviral particles
MedComm·2023· 7 citedOpen Access
Astrocytic response mediated by the CLU risk allele inhibits OPC proliferation and myelination in a human iPSC model
Cell Reports·2023· 28 citedOpen Access
Developing Hypoimmunogenic Human iPSC‐Derived Oligodendrocyte Progenitor Cells as an Off‐The‐Shelf Cell Therapy for Myelin Disorders
Advanced Science·2023· 28 citedOpen Access
Reassessing the Abundance of miRNAs in the Human Pancreas and Rodent Cell Lines and Its Implication
Non-Coding RNA·2023· 4 citedOpen Access
Viral and Host Small RNA Response to SARS-CoV-2 Infection
Microbiology Research·2022· 5 citedOpen Access
Reassessing the abundance of miRNAs in the human pancreas and rodent cell lines and its implication
2022· 1 citedOpen Access
Therapeutic development for Canavan disease using patient iPSCs introduced with the wild-type ASPA gene
iScience·2022· 14 citedOpen Access
Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection
iScience·2021· 5 citedOpen Access
Comparative transcriptomic analysis of SARS-CoV-2 infected cell model systems reveals differential innate immune responses
Scientific Reports·2021· 42 citedOpen Access
Targeting PUS7 suppresses tRNA pseudouridylation and glioblastoma tumorigenesis
Nature Cancer·2021· 155 citedOpen Access
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
Cell stem cell·2021· 219 citedOpen Access
Stem Cell Therapy: Cell‐Based Therapy for Canavan Disease Using Human iPSC‐Derived NPCs and OPCs (Adv. Sci. 23/2020)
Advanced Science·2020· 1 citedOpen Access
Cell‐Based Therapy for Canavan Disease Using Human iPSC‐Derived NPCs and OPCs
Advanced Science·2020· 31 citedOpen Access
GFAP Mutations in Astrocytes Impair Oligodendrocyte Progenitor Proliferation and Myelination in an hiPSC Model of Alexander Disease
Cell stem cell·2018· 132 citedOpen Access
Differences in silencing of mismatched targets by sliced versus diced siRNAs
Nucleic Acids Research·2018· 15 citedOpen Access
A Simple and Cost-Effective Approach for In Vitro Production of Sliced siRNAs as Potent Triggers for RNAi
Molecular Therapy — Nucleic Acids·2017· 12 citedOpen Access
m6A RNA Methylation Regulates the Self-Renewal and Tumorigenesis of Glioblastoma Stem Cells
Cell Reports·2017· 1.3k citedOpen Access
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Frequent Co-authors

Yanhong Shi(18), John J. Rossi(17), Qi Cui(14), Arthur D. Riggs(13), Erpo Tian(9), Jianfei Chao(9), Xiwei Wu(8), Yun Yen(7), Lizhao Feng(7), Peng Ye(6), Guoqiang Sun(6), Cheng Wang(6), Xianwei Chen(6), Vaithilingaraja Arumugaswami(6), Haitang Li(5), Mingzi Zhang(5), Gustavo Garcia(5), Jeremy Klein(4), Olivia Sun(4), Tao Zhou(4)