Loı̈c Dupré

Centre National de la Recherche Scientifique — France

Immunology and Microbiology · Life Sciences

40h-index4.3kcitations146works2.42yr avg
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Research Topics

T-cell and B-cell Immunology(32), Immune Cell Function and Interaction(32), Chronic Lymphocytic Leukemia Research(31), CAR-T cell therapy research(24), Immunotherapy and Immune Responses(20)

Publications146 total

Protein palmitoylation and sphingolipid metabolism control regulated exocytosis in cytotoxic lymphocytes
Science Immunology·2025· 1 cited
Immune-related actinopathies at the cross-road of immunodeficiency, autoimmunity and autoinflammation
Nature reviews. Immunology·2025· 2 cited
Clinical and molecular findings in actin-related inborn errors of immunity: the middle East and North Africa registry
Frontiers in Genetics·2025Open Access
In vitro morphological profiling of T cells predicts clinical response to natalizumab therapy in patients with multiple sclerosis
Nature Communications·2025· 1 citedOpen Access
The multiple sclerosis associated CD226 risk variant alters vitamin D-induced human type I regulatory T cell differentiation by impairing LFA-1 activation
2025Open Access
Immunoactinopathies revisited: understanding clinical manifestations and biological pathways
Blood·2025· 4 citedOpen Access
Molecular and functional characterization of the first human gain of function variant in LCK
SPIRE - Sciences Po Institutional REpository·2024
Deconstructing CTL-mediated autoimmunity through weak TCR-cross-reactivity towards highly abundant self-antigen
2024Open Access
New pharmacodynamic parameters linked with ibrutinib responses in chronic lymphocytic leukemia: Prospective study in real-world patients and mathematical modeling
PLoS Medicine·2024· 1 citedOpen Access
Morphological profiling of T cells predicts clinical response to VLA-4-targeting natalizumab therapy in patients with multiple sclerosis
2024Open Access
Mechanisms underlying skin inflammation of DOCK8 deficiency
Journal of Allergy and Clinical Immunology·2024· 4 citedOpen Access
Gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice
Methods in cell biology·2024
Coordinated ARP2/3 and glycolytic activities regulate the morphological and functional fitness of human CD8+ T cells
Cell Reports·2024· 5 citedOpen Access
LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity
Nature Communications·2024· 18 citedOpen Access
LFA-1 nanoclusters integrate TCR stimulation strength to tune T-cell cytotoxic activity
Figshare·2024Open Access
Human DOCK11 Deficiency Causes Defective Erythropoiesis and Systemic Inflammation
Blood·2023· 1 cited
159 Regulation of T cell functions by cytoskeletal proteins in the melanoma tumor microenvironment
Journal of Investigative Dermatology·2023Open Access
Lymphocyte migration and retention properties affected by ibrutinib in chronic lymphocytic leukemia
Haematologica·2023· 12 citedOpen Access
Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency
New England Journal of Medicine·2023· 31 citedOpen Access
Biallelic <i>NFATC1</i> mutations cause an inborn error of immunity with impaired CD8+ T-cell function and perturbed glycolysis
Blood·2023· 10 citedOpen Access
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Frequent Co-authors

Alessandro Aiuti(10), Kaan Boztuǧ(8), A Capron(7), Gilles Riveau(7), Sara Trifari(6), Francesco Marangoni(6), Samantha Scaramuzza(6), Maria-Grazia Roncarolo(6), Laurène Pfajfer(6), Salvatore Valitutti(6), Camille Locht(5), Anna Villa(4), Stuart G. Tangye(4), Javier Rey-Barroso(4), Johannes B. Huppa(4), Anne Galy(4), Jörg Menche(4), Laurent Kremer(4), Silvana Martino(3), Maria Grazia Roncarolo(3)