Thomas Tuschl

Rockefeller University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

121h-index105.6kcitations384works7.02yr avg
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Research Topics

MicroRNA in disease regulation(162), RNA Research and Splicing(97), RNA modifications and cancer(90), Cancer-related molecular mechanisms research(80), RNA and protein synthesis mechanisms(66)

Publications379 total

Plasma exRNA Profiling for Pregnancy Monitoring and Non-Invasive Diagnostics of Preeclampsia
Placenta·2025
Discovery, Optimization, and Evaluation of Non-Nucleoside SARS-CoV-2 NSP14 Inhibitors
Journal of Medicinal Chemistry·2025· 1 citedOpen Access
A human-mouse atlas of intrarenal myeloid cells identifies conserved disease-associated macrophages in lupus nephritis
The Journal of Experimental Medicine·2025· 4 citedOpen Access
Discovery of Novel Isofunctional SARS-CoV-2 NSP14 RNA Cap Methyltransferase Inhibitors by Structure-Based Virtual Screening
ACS Medicinal Chemistry Letters·2025Open Access
Codon-dependent regulation of mRNA translation and stability by ZC3H7A and ZC3H7B RNA-binding proteins
2025Open Access
Structural insight into the cGAS active site explains differences between therapeutically relevant species
Communications Chemistry·2025· 10 citedOpen Access
The spatially informed mFISHseq assay resolves biomarker discordance and predicts treatment response in breast cancer
Nature Communications·2025· 6 citedOpen Access
Small-molecule inhibition of SARS-CoV-2 NSP14 RNA cap methyltransferase
Nature·2024· 35 cited
Soluble urine activated leukocyte cell adhesion molecule is a strong predictor of lupus nephritis
Lara D. Veeken·2024· 6 citedOpen Access
SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas
Cell Host & Microbe·2024Open Access
Ribosome Quality Control mitigates the cytotoxicity of ribosome collisions induced by 5-Fluorouracil
Nucleic Acids Research·2024· 11 citedOpen Access
1009 In-depth analysis of myeloid cell subsets in lupus nephritis kidneys provides insights into disease mechanisms: lessons from the accelerating medicines partnership (AMP) in RA/SLE consortium
2024Open Access
Ribosome Quality Control Mechanism Mitigates the Cytotoxic Impacts of Ribosome Collisions Induced by 5-Fluorouracil
2023· 2 citedOpen Access
Multiplexed RNA-FISH-guided Laser Capture Microdissection RNA Sequencing Improves Breast Cancer Molecular Subtyping, Prognostic Classification, and Predicts Response to Antibody Drug Conjugates
2023· 3 citedOpen Access
Sleep-Related Hypoxia, Right Ventricular Dysfunction, and Survival in Patients With Group 1 Pulmonary Arterial Hypertension
Journal of the American College of Cardiology·2023· 25 citedOpen Access
Arabinose- and xylose-modified analogs of 2′,3′-cGAMP act as STING agonists
Cell chemical biology·2023· 10 citedOpen Access
SINE RNA of the imprinted miRNA clusters mediates constitutive type III interferon expression and antiviral protection in hemochorial placentas
Cell Host & Microbe·2023· 23 citedOpen Access
In vivo PAR-CLIP (viP-CLIP) of liver TIAL1 unveils targets regulating cholesterol synthesis and secretion
Nature Communications·2023· 13 citedOpen Access
Supplementary Table S3 from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
2023Open Access
Supplementary Figure S1 from Deep Sequencing Reveals a Novel miR-22 Regulatory Network with Therapeutic Potential in Rhabdomyosarcoma
2023Open Access
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Frequent Co-authors

Chris Sander(8), Markus Landthaler(8), Mihaela Zavolan(8), Dinshaw J. Patel(7), Mariana Lagos‐Quintana(6), Robert P. Sheridan(6), Sébastien Pfeffer(6), Minchen Chien(6), James J. Russo(6), Pablo Landgraf(5), Markus Hafner(5), Manuel Ascano(5), Gunter Meister(5), Sayda M. Elbashir(4), Winfried Lendeckel(4), Abdullah Yalçın(4), Alexei A. Aravin(4), Debora S. Marks(4), Gunther Hartmann(4), Jens Harborth(3)