John C. Marioni

European Bioinformatics Institute — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

103h-index54.9kcitations376works15.32yr avg
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Research Topics

Single-cell and spatial transcriptomics(167), Gene Regulatory Network Analysis(44), Cell Image Analysis Techniques(44), Gene expression and cancer classification(43), RNA Research and Splicing(33)

Publications370 total

Spatiotemporal cellular map of the developing human reproductive tract
Nature·2025· 1 citedOpen Access
Constructing the spatiotemporal atlas of single-cell lineage trajectories in stereotypic biological structures
iScience·2025Open Access
Photoinactivation of Leishmania amazonensis by Soranjidiol and white LED: Unraveling photodynamic and cell death mechanisms
Bioorganic Chemistry·2025
A spatiotemporal atlas of mouse gastrulation and early organogenesis to explore axial patterning and project in vitro models onto in vivo space
Cell Reports·2025· 3 citedOpen Access
A single-cell and tissue-scale analysis suite resolves Mixl1’s role in heart development
iScience·2025Open Access
Lab-in-the-loop therapeutic antibody design with deep learning
2025· 20 citedOpen Access
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
A novel human fetal lung-derived alveolar organoid model reveals mechanisms of surfactant protein C maturation relevant to interstitial lung disease
The EMBO Journal·2025· 13 citedOpen Access
Consortium Author List from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
Cancer Discovery·2025· 3 citedOpen Access
Data from Cancer Research in the Age of Spatial Omics: Lessons from IMAXT
2025Open Access
Gliomagenesis mimics an injury response orchestrated by neural crest-like cells
Nature·2025· 27 citedOpen Access
A Spatiotemporal Atlas of Mouse Gastrulation and Early Organogenesis to Explore Axial Patterning and Project <i>In Vitro</i> Models onto <i>In Vivo</i> Space
2024Open Access
A spatial human thymus cell atlas mapped to a continuous tissue axis
Nature·2024· 61 citedOpen Access
Spatiotemporal map of the developing human reproductive tract at single-cell resolution
2024· 1 citedOpen Access
Base editing screens define the genetic landscape of cancer drug resistance mechanisms
Nature Genetics·2024· 43 citedOpen Access
Early human lung immune cell development and its role in epithelial cell fate
2024
Multi-omic lineage tracing predicts the transcriptional, epigenetic and genetic determinants of cancer evolution
Nature Communications·2024· 9 citedOpen Access
Leveraging neighborhood representations of single-cell data to achieve sensitive DE testing with miloDE
Genome biology·2024· 17 citedOpen Access
EmptyDropsMultiome discriminates real cells from background in single-cell multiomics assays
Genome biology·2024· 2 citedOpen Access
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Frequent Co-authors

Sarah A. Teichmann(16), Oliver Stegle(11), Aaron T. L. Lun(6), Aleksandra A. Kolodziejczyk(6), Ricard Argelaguet(6), Antonio Scialdone(6), Davis J. McCarthy(5), Jong Kim(5), Florian Buettner(5), Wolf Reik(5), Berthold Göttgens(5), Yoav Gilad(4), Michael D. Morgan(4), Simon Tavaré(4), Catalina A. Vallejos(4), Kedar Nath Natarajan(4), Karsten Bach(4), Jennifer Nichols(4), Emma Dann(4), Matthew Stephens(3)