Jorge G. Quintero

Medicine · Health Sciences

6h-index147citations9works0.02yr avg
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Research Topics

Cytokine Signaling Pathways and Interactions(3), Hepatitis C virus research(2), Rheumatoid Arthritis Research and Therapies(2), Hepatitis B Virus Studies(2), Clostridium difficile and Clostridium perfringens research(2)

Publications9 total

Design, synthesis, and structure-activity relationship of a bicyclic HBV capsid assembly modulator chemotype leading to the identification of clinical candidate AB-506
Bioorganic & Medicinal Chemistry Letters·2023· 6 cited
Preclinical activity of small-molecule oral PD-L1 checkpoint inhibitors capable of reinvigorating T cell responses from chronic hepatitis B patients
Journal of Hepatology·2022· 1 cited
Preclinical anti-tumor activity of small-molecule oral PD-L1 checkpoint inhibitors.
Journal of Clinical Oncology·2022· 1 cited
Synthesis and SAR studies of novel benzodiazepinedione-based inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB)
Bioorganic & Medicinal Chemistry Letters·2018· 9 citedOpen Access
Identification and initial optimization of inhibitors of Clostridium difficile (C. difficile) toxin B (TcdB)
Bioorganic & Medicinal Chemistry Letters·2018· 9 citedOpen Access
Selective functional inhibition of JAK‐3 is sufficient for efficacy in collagen‐induced arthritis in mice
Arthritis & Rheumatism·2010· 74 cited
2-Benzimidazolyl-9-(chroman-4-yl)-purinone derivatives as JAK3 inhibitors
Bioorganic & Medicinal Chemistry Letters·2009· 18 citedOpen Access
The novel and selective JAK3 inhibitor WYE-152038 is highly efficacious in a mouse model of rheumatoid arthritis
Cytokine·2009
Small molecule antagonists of the bradykinin B1 receptor
Immunopharmacology·1999· 29 cited

Frequent Co-authors

Andrew G. Cole(7), Maria L. Webb(6), Michael Ohlmeyer(4), Tsung H. Lin(3), Elizabeth Quadros(3), Kenneth C. Appell(3), Yuefei Shao(3), Earl F. Kimble(3), Ilana L. Stroke(3), Jeffrey J. Letourneau(3), Steven G. Kultgen(3), Kristi Fan(3), Kim Stever(3), Emily P. Thi(3), Troy O. Harasym(3), Michael J. Sofia(3), Martin Hegen(2), Cheryl Nickerson‐Nutter(2), Steve Tam(2), Bojing Wang(2)