Jung‐Il Chae

Korea Research Institute of Bioscience and Biotechnology — South Korea

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

31h-index2.6kcitations99works0.02yr avg
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Research Topics

Pharmacological Effects of Natural Compounds(18), Pluripotent Stem Cells Research(10), Plant-derived Lignans Synthesis and Bioactivity(9), Cell death mechanisms and regulation(8), Ginseng Biological Effects and Applications(7)

Publications99 total

Drug-induced gastrointestinal toxicity and barrier integrity: cytoskeleton-mediated impairment in a clinically relevant human intestinal epithelium model
Experimental & Molecular Medicine·2026Open Access
Picropodophyllotoxin: A Natural Epimer Targeting STAT3 Phosphorylation and ROS-Mediated Apoptosis in Oral Squamous Cell Carcinoma Cells
Biocell·2025Open Access
Neuroprotective Effects of Licochalcone D in Oxidative-Stress-Induced Primitive Neural Stem Cells from Parkinson’s Disease Patient-Derived iPSCs
Biomedicines·2023· 9 citedOpen Access
Corrigendum to: Deoxypodophyllotoxin Induces ROSMediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
Journal of Microbiology and Biotechnology·2022Open Access
Acceleration of Mesenchymal-to-Epithelial Transition (MET) during Direct Reprogramming Using Natural Compounds
Journal of Microbiology and Biotechnology·2022· 2 citedOpen Access
Deoxypodophyllotoxin Induces ROS-Mediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
Journal of Microbiology and Biotechnology·2022· 10 citedOpen Access
Continuous centrifugal microfluidics (CCM) isolates heterogeneous circulating tumor cells via full automation
Theranostics·2022· 34 citedOpen Access
Licochalcone H Induces Cell Cycle Arrest and Apoptosis in Human Skin Cancer Cells by Modulating JAK2/STAT3 Signaling
Biomolecules & Therapeutics·2021· 16 citedOpen Access
Podophyllotoxin Induces ROS-Mediated Apoptosis and Cell Cycle Arrest in Human Colorectal Cancer Cells via p38 MAPK Signaling
Biomolecules & Therapeutics·2021· 30 citedOpen Access
Picropodophyllotoxin Induces G1 Cell Cycle Arrest and Apoptosis in Human Colorectal Cancer Cells via ROS Generation and Activation of p38 MAPK Signaling Pathway
Journal of Microbiology and Biotechnology·2021· 16 citedOpen Access
The 3-deoxysappanchalcone induces ROS-mediated apoptosis and cell cycle arrest via JNK/p38 MAPKs signaling pathway in human esophageal cancer cells
Phytomedicine·2021· 62 cited
Deoxypodophyllotoxin Inhibits Cell Growth and Induces Apoptosis by Blocking EGFR and MET in Gefitinib-Resistant Non-Small Cell Lung Cancer
Journal of Microbiology and Biotechnology·2021· 19 citedOpen Access
Quantitative Proteomic Analysis of Primitive Neural Stem Cells from LRRK2 G2019S-Associated Parkinson’s Disease Patient-Derived iPSCs
Life·2020· 9 citedOpen Access
Overexpression of cytochrome P450 2J2 and exogenous 11,12-EET suppress ER stress-induced apoptosis and promote autophagy in DM-induced rats
Atherosclerosis·2020
Targeted inhibition of c-MET by podophyllotoxin promotes caspase-dependent apoptosis and suppresses cell growth in gefitinib-resistant non-small cell lung cancer cells
Phytomedicine·2020· 24 cited
Deoxypodophyllotoxin, a Lignan from Anthriscus sylvestris, Induces Apoptosis and Cell Cycle Arrest by Inhibiting the EGFR Signaling Pathways in Esophageal Squamous Cell Carcinoma Cells
International Journal of Molecular Sciences·2020· 15 citedOpen Access
Alternative Options for Skin Cancer Therapy via Regulation of AKT and Related Signaling Pathways
International Journal of Molecular Sciences·2020· 34 citedOpen Access
Picropodophyllotoxin, an Epimer of Podophyllotoxin, Causes Apoptosis of Human Esophageal Squamous Cell Carcinoma Cells Through ROS-Mediated JNK/P38 MAPK Pathways
International Journal of Molecular Sciences·2020· 20 citedOpen Access
Janus kinase 2 inhibition by Licochalcone B suppresses esophageal squamous cell carcinoma growth
Phytotherapy Research·2020· 23 cited
Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET
Biomolecules·2020· 45 citedOpen Access
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Frequent Co-authors

Jung‐Hyun Shim(38), Goo Yoon(18), Mee‐Hyun Lee(14), Ha‐Na Oh(14), Jin Hyoung Cho(13), Seung‐Sik Cho(13), Young‐Joo Jeon(11), Ah‐Won Kwak(8), Young Sik Cho(7), Eunae Kim(7), Ji‐Hye Seo(7), Kangdong Liu(6), Seon‐Min Park(5), Hyung‐Min Chung(4), Deog‐Bon Koo(4), Yung Hyun Choi(4), Jae‐Cheon Shin(4), Nag‐Jin Choi(4), Ra Ham Lee(4), Woong Bang(4)