Michael Doubek

Central European Institute of Technology — Czech Republic

Medicine · Health Sciences

44h-index7.4kcitations813works6.82yr avg
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Research Topics

Chronic Lymphocytic Leukemia Research(444), Lymphoma Diagnosis and Treatment(162), Acute Lymphoblastic Leukemia research(105), Chronic Myeloid Leukemia Treatments(94), Immunodeficiency and Autoimmune Disorders(84)

Publications808 total

Treatability with ibrutinib plus venetoclax in patients with CLL in the real-world. the eric international thrive study
Blood·2025Open Access
Clinical value of advanced genomic testing in adult Philadelphia-negative B-ALL: Results from the CZ national leukemia study group (CELL)
Blood·2025Open Access
Dose and BTK occupancy relationship in the prospective Phase 2 TAILOR study: Exploratory end point analysis of the ibrutinib monotherapy cohorts in patients with previously untreated chronic lymphocytic leukemia
Blood·2025Open Access
Survival differences of patients with treatment-naive CLL between the chemoimmunotherapy and BTKi eras: An eric study.
Blood·2025
Longitudinal immune monitoring in patients treated with CD19 and BCMA CAR-T cells using standardized 8‑color flow cytometry panel reveals substantial differences among products kinetics and persistence
Blood·2025Open Access
Genome-wide CRISPR screening identifies CRL1 as a therapeutic target for restoring CD19 expression and improving immunotherapy efficacy in  B-cell malignancies
Blood·2025Open Access
Central nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL
Blood Advances·2025Open Access
Clinical and transcriptomic characterization of patients with chronic lymphocytic leukemia harboring t(14;19): an ERIC study
Leukemia·2025· 1 citedOpen Access
Recommendations for chronic lymphocytic leukaemia diagnosis and therapy
Transfuze a hematologie dnes·2025
CLL-984: CLL18/MOIRAI International Phase 3 Trial: Aiming to Establish Measurement of Individual Residual Disease for Adjustment of Treatment Duration to Improve Outcomes in First-Line Treatment of CLL/SLL
Clinical Lymphoma Myeloma & Leukemia·2025· 2 cited
POSTER: CLL-984 CLL18/MOIRAI International Phase 3 Trial: Aiming to Establish Measurement of Individual Residual Disease for Adjustment of Treatment Duration to Improve Outcomes in First-Line Treatment of CLL/SLL
Clinical Lymphoma Myeloma & Leukemia·2025
Assessing an eHealth Intervention on Quality of Life in Patients With Chronic Lymphocytic Leukemia and Myelodysplastic Syndromes: The MyPal Randomized Controlled Trial
JCO Oncology Practice·2025
Germline Jak2-R1063H mutation interferes with normal hematopoietic development and increases risk of thrombosis and leukemic transformation
Leukemia·2025· 2 citedOpen Access
Circular RNA signature of aggressive CLL with t(14;19)(q32;q13). An ERIC study
Journal of Hematology & Oncology·2025· 1 citedOpen Access
The necessity of geneticist and pulmonologist collaboration in the treatment of monogenic interstitial lung diseases in adults
Breathe·2025· 1 citedOpen Access
Disease-specific U1 spliceosomal RNA mutations in mature B-cell neoplasms
Leukemia·2025· 1 citedOpen Access
OT02 | CLL18/MOIRAI TRIAL AIMING TO ESTABLISH MEASUREMENT OF INDIVIDUAL RESIDUAL DISEASE FOR ADJUSTMENT OF TREATMENT DURATION TO IMPROVE OUTCOMES IN TREATMENT‐NAIVE CLL/SLL
Hematological Oncology·2025Open Access
Endoplasmic reticulum stress disrupts signaling via altered processing of transmembrane receptors
Cell Communication and Signaling·2025· 3 citedOpen Access
Blinatumomab in induction therapy improves molecular response in untreated adults with Ph- B-cell precursor acute lymphoblastic leukemia
Haematologica·2025Open Access
Prognostic impact of expression of CD2, CD25, and/or CD30 in/on mast cells in systemic mastocytosis: a registry study of the European Competence Network on Mastocytosis
Leukemia·2025· 3 citedOpen Access
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Frequent Co-authors

Šárka Pospı́šilová(20), Jiřı́ Mayer(19), Yvona Brychtová(13), Chiara Elena(9), Andreas Reiter(8), Olivier Hermine(8), Hans Hägglund(8), Wolfgang R. Sperr(8), Peter Valent(8), Marek Mráz(8), Mattias Mattsson(8), Luca Malcovati(8), Karla Plevová(7), Nicola Gökbuget(7), Sebastian Giebel(7), Boris Tichý(7), Martin Trbušek(7), Aleksandra Górska(7), Marek Niedoszytko(7), Roberta Zanotti(7)