Gregory B. Waypa

Northwestern University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index3.7kcitations40works5.52yr avg
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Research Topics

Mitochondrial Function and Pathology(18), Nitric Oxide and Endothelin Effects(13), Cancer, Hypoxia, and Metabolism(11), Pulmonary Hypertension Research and Treatments(7), Cardiac Ischemia and Reperfusion(7)

Publications40 total

LncRNA H19 Upregulation Links Hypoplastic Left Heart Syndrome to Impaired PINK1/Parkin-Mediated Mitophagy and Ischemic Vulnerability
2025· 1 citedOpen Access
Abstract 4367268: Regulatory LncRNA H19 and mitophagy in hypoplastic left heart syndrome and in immature ischemic/reperfused rodent hearts
Circulation·2025
Abstract 4138062: Pharmacological inhibition of HDAC6 improves post-infarction cardiac function by limiting mitochondrial fission in type 2 diabetic mice
Circulation·2024
Mitochondria regulate proliferation in adult cardiac myocytes
Journal of Clinical Investigation·2024· 21 citedOpen Access
Role of Hypoxia-Inducible Factors in Regulating Right Ventricular Function and Remodeling during Chronic Hypoxia–induced Pulmonary Hypertension
American Journal of Respiratory Cell and Molecular Biology·2020· 47 citedOpen Access
Roles of HIF1 and HIF2 in pulmonary hypertension: it all depends on the context
European Respiratory Journal·2019· 25 citedOpen Access
Mitochondrial Complex III regulates proliferative arrest in postnatal cardiomyocytes
PEDIATRICS·2018
Mitochondrial Complex III regulates proliferative arrest in postnatal cardiomyocytes
PEDIATRICS·2018
Loss of Hypoxia Inducible Factor‐1α Increases Right Ventricular Hypertrophy in Chronic Hypoxia‐Induced Pulmonary Hypertension
The FASEB Journal·2018
JNK2 up-regulates hypoxia-inducible factors and contributes to hypoxia-induced erythropoiesis and pulmonary hypertension
Journal of Biological Chemistry·2017· 24 citedOpen Access
Aberrant cGMP signaling persists during recovery in mice with oxygen-induced pulmonary hypertension
PLoS ONE·2017· 12 citedOpen Access
Redox signaling during hypoxia in mammalian cells
Redox Biology·2017· 193 citedOpen Access
MP PLOS One manuscript data.pdf
Figshare·2017Open Access
O 2 sensing, mitochondria and ROS signaling: The fog is lifting
Molecular Aspects of Medicine·2016· 190 citedOpen Access
Regulation of Hypoxia-induced Pulmonary Hypertension by Vascular Smooth Muscle Hypoxia-Inducible Factor-1α
American Journal of Respiratory and Critical Care Medicine·2013· 251 cited
Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
Journal of Visualized Experiments·2013· 16 citedOpen Access
Isolation of Pulmonary Artery Smooth Muscle Cells from Neonatal Mice
Journal of Visualized Experiments·2013· 4 cited
Peroxiredoxin-5 targeted to the mitochondrial intermembrane space attenuates hypoxia-induced reactive oxygen species signalling
Biochemical Journal·2013· 60 citedOpen Access
Sirtuin 3 Deficiency Does Not Augment Hypoxia-Induced Pulmonary Hypertension
American Journal of Respiratory Cell and Molecular Biology·2013· 30 citedOpen Access
Superoxide Generated at Mitochondrial Complex III Triggers Acute Responses to Hypoxia in the Pulmonary Circulation
American Journal of Respiratory and Critical Care Medicine·2013· 152 citedOpen Access
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Frequent Co-authors

Paul T. Schumacker(32), Paul T. Mungai(9), Jeremy D. Marks(9), V. Joseph Dudley(7), Robert D. Guzy(6), Danijela Đokić(5), Kimberly A. Smith(5), Kathryn N. Farrow(5), Navdeep S. Chandel(4), Sara K. Berkelhamer(4), Terry L. Vanden Hoek(4), Edward B. Thorp(4), Keng Jin Lee(4), Molly K. Ball(3), Lyubov Czech(3), Fred L. Minnear(3), G. R. Scott Budinger(3), Gastón Ofman(3), Xuebin Fu(3), A.S.K. Sinha(3)