Bernadette Breiden

University of Bonn — Germany

Medicine · Health Sciences

28h-index2.8kcitations42works0.02yr avg
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Research Topics

Lysosomal Storage Disorders Research(24), Cellular transport and secretion(15), Sphingolipid Metabolism and Signaling(14), Lipid Membrane Structure and Behavior(8), Glycosylation and Glycoproteins Research(6)

Publications42 total

Corrigendum to: Emerging mechanisms of drug-induced phospholipidosis
Biological Chemistry·2021· 1 cited
Acid Sphingomyelinase, a Lysosomal and Secretory Phospholipase C, Is Key for Cellular Phospholipid Catabolism
International Journal of Molecular Sciences·2021· 52 citedOpen Access
Mechanism of Secondary Ganglioside and Lipid Accumulation in Lysosomal Disease
International Journal of Molecular Sciences·2020· 79 citedOpen Access
Emerging mechanisms of drug-induced phospholipidosis
Biological Chemistry·2019· 173 citedOpen Access
Lysosomal Glycosphingolipid Storage Diseases
Annual Review of Biochemistry·2019· 149 cited
Ganglioside GM2 catabolism is inhibited by storage compounds of mucopolysaccharidoses and by cationic amphiphilic drugs
Molecular Genetics and Metabolism·2019· 16 cited
Membrane lipids and their degradation compounds control GM2 catabolism at intralysosomal luminal vesicles
Journal of Lipid Research·2019· 18 citedOpen Access
Inactivation of ceramide synthase 2 catalytic activity in mice affects transcription of genes involved in lipid metabolism and cell division
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2018· 23 cited
Ceramide Synthase Schlank Is a Transcriptional Regulator Adapting Gene Expression to Energy Requirements
Cell Reports·2018· 55 citedOpen Access
Ganglioside Metabolism and Its Inherited Diseases
Methods in molecular biology·2018· 30 cited
Synthetic Glycoforms Reveal Carbohydrate‐Dependent Bioactivity of Human Saposin D
Angewandte Chemie·2017· 13 cited
Synthetic Glycoforms Reveal Carbohydrate‐Dependent Bioactivity of Human Saposin D
Angewandte Chemie International Edition·2017· 34 cited
Identification of a feedback loop involving β-glucosidase 2 and its product sphingosine sheds light on the molecular mechanisms in Gaucher disease
Journal of Biological Chemistry·2017· 26 citedOpen Access
Lipids regulate the hydrolysis of membrane bound glucosylceramide by lysosomal β-glucocerebrosidase
Journal of Lipid Research·2017· 49 citedOpen Access
Cytoskeletal defects in GBA2 knockout-testis already occur during the first spermatogenic wave.
Figshare·2015Open Access
Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer
Journal of Lipid Research·2015· 23 citedOpen Access
Membrane lipids regulate ganglioside GM2 catabolism and GM2 activator protein activity
Journal of Lipid Research·2015· 38 citedOpen Access
Accumulation of Glucosylceramide in the Absence of the Beta-Glucosidase GBA2 Alters Cytoskeletal Dynamics
PLoS Genetics·2015· 39 citedOpen Access
Acid sphingomyelinase activity is regulated by membrane lipids and facilitates cholesterol transfer by NPC2
Journal of Lipid Research·2014· 77 citedOpen Access
The role of sphingolipid metabolism in cutaneous permeabilitybarrier formation
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids·2013· 172 cited
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Frequent Co-authors

Konrad Sandhoff(40), Günter Schwarzmann(8), Roch‐Philippe Charles(3), Edith Hümmler(3), Irfan Y. Tamboli(3), Jochen Walter(3), Reinhard Bauer(3), Jonathan O. Babalola(3), Silvia Locatelli‐Hoops(3), Natascha Remmel(3), Güenter Schwarzmann(3), Sophie Schonauer(3), Peter Dörmann(3), Yildiz Yildiz(3), Dagmar Wachten(3), Susi Anheuser(3), Céline Leyvraz(2), Marjorie Guitard(2), Samuel Rotman(2), Jean‐Christophe Stehle(2)