Guang‐Bo Ge

Shanghai Innovative Research Center of Traditional Chinese Medicine — China

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

52h-index9.0kcitations350works4.72yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(99), Computational Drug Discovery Methods(52), Cholinesterase and Neurodegenerative Diseases(49), Drug Transport and Resistance Mechanisms(38), Pharmacological Effects of Natural Compounds(30)

Publications350 total

Novel Vascularized Human Liver Organoids for Modeling Alcohol‐Induced Liver Injury and Developing Hepatoprotective Therapy
Advanced Science·2025· 1 citedOpen Access
Yujie recipe attenuates bleomycin-induced pulmonary fibrosis via suppressing NF-κB/NLRP3 signaling in a Nrf2-dependent manner
Phytomedicine·2025· 1 cited
Super-Absorbing Quantum-Confined Cyanine Dyes for Near-Infrared Confocal Imaging of Hierarchical Nephron Structures
Journal of the American Chemical Society·2025
The Identification and Synthesis of New Sea Cucumber Peptides Leveraging Peptidomics Technology, along with their Anti-Parkinson’s Disease Efficacy
Journal of Neuroimmune Pharmacology·2025
Isoliquiritigenin attenuates cisplatin-induced hearing loss and ototoxicity by activating the Keap1-Nrf2-ARE pathway
Free Radical Biology and Medicine·2025· 2 cited
Design and Synthesis of Senescence-Targeted Prodrugs with Senomorphic and Senolytic Properties To Mitigate Chemotherapy-Induced Kidney Injury
Journal of Medicinal Chemistry·2025
Macrophage-targeted polysaccharide nano-immunomodulators with spatial- and time-programmed drug release for cancer therapy
Nano Today·2025Open Access
Discovery of orally active and serine-targeting covalent inhibitors against hCES2A for ameliorating irinotecan-triggered gut toxicity
Acta Pharmaceutica Sinica B·2025· 1 citedOpen Access
To elucidate the effect of Ruanjian Qingmai granules on arteriosclerosis obliterans from the perspective of cholesterol efflux
Frontiers in Medicine·2025· 1 citedOpen Access
Nanobody-based dual-mode sensing platform for highly sensitive detection of aflatoxin B1
Biosensors and Bioelectronics·2025· 5 cited
[Research progress in pharmacological activities and pharmacokinetics of geniposidic acid].
PubMed·2025
Discovery of a novel chalcone-derived covalent Keap1 binder for mitigating cisplatin-induced mitochondrial dysfunction and nephrotoxicity
Redox Biology·2025· 7 citedOpen Access
A light-controlled dextran nano-immunomodulator amplifies immunogenic cell death for cancer immunotherapy
Carbohydrate Polymers·2025· 5 cited
Discovery of a Novel Serine-Targeting Covalent Inhibitor against HCES2A for Treating Drug-induced Diarrhea and Ulcerative Colitis
Journal of Medicinal Chemistry·2025· 1 cited
Pectolinarigenin mitigates 5-FU-induced intestinal mucositis via suppressing ferroptosis through activating PPARγ/GPX4 signaling
Phytomedicine·2025· 9 cited
Discovery of baicalein derivatives as novel covalent inhibitors of SARS CoV-2 Mpro: Structure-activity relationships and inhibitory mechanisms
Bioorganic Chemistry·2025· 3 cited
Rational engineering of an isoform-specific and sensitive turn-on estrogen sulfotransferase-activatable fluorescent probe for functional sensing and drug discovery
Chinese Chemical Letters·2025· 2 cited
The role of Salvia miltiorrhiza compounds in hepatocellular carcinoma: a preliminary investigation based on computational analysis and liquid chromatography-tandem mass spectrometry
Current Pharmaceutical Analysis·2025· 6 citedOpen Access
Polysaccharide Nanoadjuvants Engineered via Phenotype-Specific Nanoprobe-Assisted Phenotypic Screen Reprogram Macrophage Cell Functions for Cancer and Rheumatoid Arthritis Therapy
ACS Nano·2025· 12 citedOpen Access
AI-Driven Discovery of Highly Specific and Efficacious hCES2A Inhibitors for Ameliorating Irinotecan-Triggered Gut Toxicity
Journal of Medicinal Chemistry·2025· 7 cited
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Frequent Co-authors

Ling Yang(29), Jie Hou(20), Lei Feng(13), Qiang Jin(12), Li‐Wei Zou(11), Jing Ning(11), Jingnan Cui(11), Ziru Dai(9), Ping Wang(8), Dandan Wang(7), Zi-Miao Weng(7), Yun‐Feng Cao(7), Tongyi Dou(6), Jie Hou(6), Xia Lv(5), Xiaochi Ma(5), Zhaoming Liu(5), Jingjing Wu(5), Xiao‐Qing Guan(5), Yanyan Zhang(5)