Hwei-Ling Cheng

Shandong University — China

Immunology and Microbiology · Life Sciences

20h-index7.3kcitations36works9.42yr avg
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Research Topics

T-cell and B-cell Immunology(14), Immune Cell Function and Interaction(12), Monoclonal and Polyclonal Antibodies Research(9), HIV Research and Treatment(8), PARP inhibition in cancer therapy(6)

Publications36 total

Hydrophobic residue substitutions enhance the stability and <i>in vivo</i> immunogenicity of respiratory syncytial virus fusion protein
Journal of Virology·2025· 2 citedOpen Access
An engineered immunogen activates diverse HIV broadly neutralizing antibody precursors and promotes acquisition of improbable mutations
Science Translational Medicine·2025· 3 cited
CGDC: A Secure External Data Collection Mechanism for Blockchain
Communications in computer and information science·2025
Author Correction: Vaccination induces broadly neutralizing antibody precursors to HIV gp41
Nature Immunology·2024· 1 citedOpen Access
Vaccination induces broadly neutralizing antibody precursors to HIV gp41
Nature Immunology·2024· 41 citedOpen Access
An in vivo method for diversifying the functions of therapeutic antibodies
Proceedings of the National Academy of Sciences·2021· 4 citedOpen Access
An In Vivo Method for Diversifying the Functions of Therapeutic Antibodies
2020Open Access
Conditional antibody expression to avoid central B cell deletion in humanized HIV-1 vaccine mouse models
Proceedings of the National Academy of Sciences·2020· 11 citedOpen Access
Conditional Antibody Expression to Avoid Central B Cell Deletion in a Humanized HIV-1 Vaccine Mouse Models
2020· 1 citedOpen Access
Targeted selection of HIV-specific antibody mutations by engineering B cell maturation
Science·2019· 172 citedOpen Access
Induction of HIV Neutralizing Antibody Lineages in Mice with Diverse Precursor Repertoires
Cell·2016· 244 citedOpen Access
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
Cell Reports·2013· 8 citedOpen Access
SIRT7 Represses Myc Activity to Suppress ER Stress and Prevent Fatty Liver Disease
Cell Reports·2013· 276 citedOpen Access
Antigenicity and immunogenicity of a novel, acute HIV-1 Tanzanian subtype C gp145 envelope protein for clinical development
Retrovirology·2012· 1 citedOpen Access
CTCF-binding elements mediate control of V(D)J recombination
Nature·2011· 267 citedOpen Access
ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks
Nature·2010· 213 citedOpen Access
Elements between the IgH variable (V) and diversity (D) clusters influence antisense transcription and lineage-specific V(D)J recombination
Proceedings of the National Academy of Sciences·2010· 35 cited
Homozygous DNA ligase IV R278H mutation in mice leads to leaky SCID and represents a model for human LIG4 syndrome
Proceedings of the National Academy of Sciences·2010· 48 citedOpen Access
Regulation of activation-induced cytidine deaminase DNA deamination activity in B-cells by Ser38 phosphorylation
Biochemical Society Transactions·2009· 16 citedOpen Access
Integrity of the AID serine-38 phosphorylation site is critical for class switch recombination and somatic hypermutation in mice
Proceedings of the National Academy of Sciences·2009· 107 citedOpen Access
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Frequent Co-authors

Frederick W. Alt(24), Ming Tian(9), Kelly McGovern(6), Mai N. Dao(5), Michael T. Kimble(5), Yiwei Chen(5), Elizabeth Cantor(5), Peyton Waddicor(5), Katrin F. Chua(4), Raúl Mostoslavsky(4), Andrew Franklin(4), Barton F. Haynes(4), Derek W. Cain(4), J. Frederic Mushinski(4), Andrew Murphy(3), George D. Yancopoulos(3), William R. Schief(3), Shan Zha(3), Aimee Williams(3), Frederick R. Blattner(3)