Christian Schwöppe

University Hospital Münster — Germany

Medicine · Health Sciences

21h-index1.8kcitations54works0.22yr avg
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Research Topics

Peptidase Inhibition and Analysis(28), Cardiac tumors and thrombi(11), Protease and Inhibitor Mechanisms(10), Cell Adhesion Molecules Research(8), Nanoplatforms for cancer theranostics(5)

Publications54 total

Trabectedin plus CD13-targeted tissue factor tTF-NGR against advanced relapsed or refractory soft tissue sarcoma: translational data, clinical safety and efficacy
Scientific Reports·2026Open Access
2711P Trabectedin plus CD13-targeted tissue factor tTF-NGR against advanced relapsed or refractory soft tissue sarcoma: Translational data, clinical safety and efficacy
Annals of Oncology·2025
Abstract 824: Comparative pharmacokinetics (PK) of targeted tissue factor tTF-NGR when intravenously applied alone or in combination with preceding trabectedin
Cancer Research·2025
Abstract 4606: Combinatorial effects of a sequence of trabectedin (T) and CD13-targeted tissue factor tTF-NGR on human vascular endothelial cells (HUVEC) and in soft tissue sarcoma (STS) models
Cancer Research·2024
Comparison of antibody-based immunotherapeutics for malignant hematological disease in an experimental murine model
Blood Advances·2024· 1 citedOpen Access
CAR T cells as micropharmacies against solid cancers: Combining effector T-cell mediated cell death with vascular targeting in a one-step engineering process
Cancer Gene Therapy·2023· 15 citedOpen Access
Abstract 3182: CAR T cells as micropharmacies to induce locoregional tumor vascular infarction by antigen-specific delivery of tissue factor to the tumor microenvironment
Cancer Research·2023
Electrostatic anti-CD33-antibody–protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia
Journal of Hematology & Oncology·2022· 21 citedOpen Access
Multiparametric Magnetic Resonance Imaging for Immediate Target Hit Assessment of CD13—Targeted Tissue Factor tTF-NGR in Advanced Malignant Disease
Cancers·2021· 7 citedOpen Access
Targeting Tissue Factor to Tumor Vasculature to Induce Tumor Infarction
Cancers·2021· 8 citedOpen Access
Animal Safety, Toxicology, and Pharmacokinetic Studies According to the ICH S9 Guideline for a Novel Fusion Protein tTF-NGR Targeting Procoagulatory Activity into Tumor Vasculature: Are Results Predictive for Humans?
Cancers·2020· 6 citedOpen Access
563P First-in-class CD13-targeted tissue factor tTF-NGR in patients with recurrent or refractory malignant tumours: Safety and pharmacokinetic results of a phase I study
Annals of Oncology·2020
Low‐density lipoprotein receptor (LDLR) is an independent adverse prognostic factor in acute myeloid leukaemia
British Journal of Haematology·2020· 24 citedOpen Access
First-In-Class CD13-Targeted Tissue Factor tTF-NGR in Patients with Recurrent or Refractory Malignant Tumors: Results of a Phase I Dose-Escalation Study
Cancers·2020· 23 citedOpen Access
Radiation synergizes with antitumor activity of CD13-targeted tissue factor in a HT1080 xenograft model of human soft tissue sarcoma
PLoS ONE·2020· 9 citedOpen Access
The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia
Leukemia·2019· 45 citedOpen Access
Selbstanordnung von BODIPY‐Farbstoffen als Werkzeug, um die Antitumoraktivität von Capsaicin bei Prostatakrebs zu erhöhen
Angewandte Chemie·2018· 6 cited
Hierarchical Self‐Assembly of BODIPY Dyes as a Tool to Improve the Antitumor Activity of Capsaicin in Prostate Cancer
Angewandte Chemie International Edition·2018· 57 cited
Aminopeptidase N (CD13): Expression, Prognostic Impact, and Use as Therapeutic Target for Tissue Factor Induced Tumor Vascular Infarction in Soft Tissue Sarcoma
Translational Oncology·2018· 22 citedOpen Access
CD13 as target for tissue factor induced tumor vascular infarction in small cell lung cancer
Lung Cancer·2017· 15 cited
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Frequent Co-authors

Wolfgang E. Berdel(41), Christoph Schliemann(31), Rolf M. Mesters(30), Torsten Keßler(27), Georg Lenz(16), Caroline Brand(16), Wolfgang Hartmann(14), Saliha Harrach(12), Eva Wardelmann(11), Heike Hintelmann(10), Carsten Müller‐Tidow(9), Linus Angenendt(8), Christoph Bremer(6), Walter Heindel(6), Rüediger Liersch(6), L. H. Schmidt(6), Andrew F. Berdel(6), Dennis Görlich(5), Janine Ring(5), Caroline Zerbst(5)