Zsuzsanna Izsvák

Max Delbrück Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

63h-index15.5kcitations257works3.92yr avg
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Research Topics

CRISPR and Genetic Engineering(158), Chromosomal and Genetic Variations(71), Virus-based gene therapy research(67), RNA Interference and Gene Delivery(63), Animal Genetics and Reproduction(42)

Publications256 total

Endogenous retroviral elements LTR8B and MER65 rewire PSG9 regulation to control trophoblast syncytialization and pre-eclampsia risk
2026Open Access
ERV3-MLT1 provides cis-regulatory elements for human placental functioning and are commonly dysregulated in human-specific preeclampsia
Genome biology·2025Open Access
Co-option of an endogenous retrovirus (LTR7-HERVH) in early human embryogenesis: becoming useful and going unnoticed
Mobile DNA·2025· 2 citedOpen Access
Effect of degeneration stage on non-viral tissue transfection of rd10 retina ex vivo
Molecular Therapy — Nucleic Acids·2025Open Access
Effect of degeneration stage on non-viral tissue transfection of rd10 retina ex vivo
JuSER Publikationsportal·2025Open Access
Non-viral targeted insertion of large payloads into T cells
Nature Biomedical Engineering·2024
Atypical KCNQ1/Kv7 channel function in a neonatal diabetes patient: Hypersecretion preceded the failure of pancreatic β-cells
iScience·2024· 6 citedOpen Access
Selection on synonymous sites: the unwanted transcript hypothesis
Nature Reviews Genetics·2024· 23 citedOpen Access
Staring at the onco-exaptation: the two-faced medley of an ancient retrovirus, HERVH
Journal of Clinical Investigation·2023· 4 citedOpen Access
A new human embryonic cell type associated with activity of young transposable elements allows definition of the inner cell mass
PLoS Biology·2023· 19 citedOpen Access
HMGXB4 Targets Sleeping Beauty Transposition to Germinal Stem Cells
International Journal of Molecular Sciences·2023· 3 citedOpen Access
Enhanced Biosafety of the Sleeping Beauty Transposon System by Using mRNA as Source of Transposase to Efficiently and Stably Transfect Retinal Pigment Epithelial Cells
Biomolecules·2023· 5 citedOpen Access
GMP-Grade Manufacturing and Quality Control of a Non-Virally Engineered Advanced Therapy Medicinal Product for Personalized Treatment of Age-Related Macular Degeneration
Biomedicines·2022· 12 citedOpen Access
ValRun: GMP-grade Manufacturing and Quality Control of a Non-Virally engineered Advanced Therapy Medicinal Product for Personalized Treatment of Age-Related Macular Degeneration
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
ValRun: GMP-grade Manufacturing and Quality Control of a Non-Virally engineered Advanced Therapy Medicinal Product for Personalized Treatment of Age-Related Macular Degeneration
Zenodo (CERN European Organization for Nuclear Research)·2022Open Access
Molecular and Functional Characterization of BDNF-Overexpressing Human Retinal Pigment Epithelial Cells Established by Sleeping Beauty Transposon-Mediated Gene Transfer
International Journal of Molecular Sciences·2022· 8 citedOpen Access
Retrotransposon: a versatile player in human preimplantation development and health
Life Medicine·2022· 9 citedOpen Access
A Novel Gene Controls a New Structure: PiggyBac Transposable Element-Derived 1, Unique to Mammals, Controls Mammal-Specific Neuronal Paraspeckles
Molecular Biology and Evolution·2022· 8 citedOpen Access
Recapitulating early human development with 8C-like cells
Cell Reports·2022· 83 citedOpen Access
Safe and efficient in vivo hematopoietic stem cell transduction in nonhuman primates using HDAd5/35++ vectors
Molecular Therapy — Methods & Clinical Development·2022· 1 citedOpen Access
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Frequent Co-authors

Zoltán Ivics(39), Lajos Mátés(11), Csaba Miskey(7), Perry B. Hackett(5), Ronald H.A. Plasterk(4), Jichang Wang(4), Manvendra Singh(4), Nina V. Fuchs(4), Ivana Grabundžija(4), Andreas Gogol‐Döring(4), Marinee Chuah(3), Thierry VandenDriessche(3), Gerald G. Schumann(3), Aron M. Geurts(3), Michal Pravenec(3), Eyayu Belay(2), Boris Jerchow(2), Katja Becker(2), Janka Mátrai(2), Alessandro Prigione(2)