Takashi Kuwabara

Yokohama University of Pharmacy — Japan

Pharmacology, Toxicology and Pharmaceutics · Life Sciences

23h-index2.7kcitations91works0.02yr avg
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Research Topics

Pharmacogenetics and Drug Metabolism(14), Drug Transport and Resistance Mechanisms(13), Cancer Treatment and Pharmacology(9), Monoclonal and Polyclonal Antibodies Research(8), Blood disorders and treatments(8)

Publications91 total

Continuous exposure to therapeutic drugs doxorubicin and vincristine reduces drug efficacy through transcriptional and post-transcriptional regulation of P-glycoprotein in follicular lymphoma
Drug Metabolism and Pharmacokinetics·2025
Antibody-based therapeutics
Drug Metabolism and Pharmacokinetics·2019· 1 cited
Biosimilarity assessment of biosimilar therapeutic monoclonal antibodies
Drug Metabolism and Pharmacokinetics·2018· 62 citedOpen Access
An iminium ion metabolite hampers the production of the pharmacologically active metabolite of a multikinase inhibitor KW‐2449 in primates: irreversible inhibition of aldehyde oxidase and covalent binding with endogenous proteins
Biopharmaceutics & Drug Disposition·2018· 8 cited
Monoamine oxidase B oxidizes a novel multikinase inhibitor KW-2449 to its iminium ion and aldehyde oxidase further converts it to the oxo-piperazine form in human
Drug Metabolism and Pharmacokinetics·2017· 11 cited
Shape-Controlled Preparation of MAPbI<sub>3</sub> Nanoparticles by Ionic Liquid-Assisted Simple Spin-coating Method with Tunable Optical Absorption
Extended Abstracts of the 2015 International Conference on Solid State Devices and Materials·2015
Flexible thin film Si solar cells and modules
International Workshop on Active-Matrix Flatpanel Displays and Devices·2013
THE HISTORY AND THE PRESENT CONDITIONS OF THE OCCUPATIONAL BLADDER CANCER IN OUR COUNTRY
The Japanese Journal of Urology·2013· 1 cited
What is Desirability in Social Behavior? : Universality and Variability in Social Norms (2)
Medical Entomology and Zoology·2012
Successful Radiofrequency Catheter Ablation of Left Anterolateral Accessory Pathway Associated with a Coronary Sinus Diverticulum Using an Irrigated-Tip Catheter
Journal of Arrhythmia·2011Open Access
LC–MS/MS coupled with immunoaffinity extraction for determination of estrone, 17β-estradiol and estrone 3-sulfate in human plasma
Journal of Chromatography B·2009· 41 cited
Risk Changed Human Being and Society: From the Viewpoint of Evolution
Medical Entomology and Zoology·2009
Development of failure detection system based on vibration signal for smart artificial heart: In vitro study
2008· 2 cited
Pharmacokinetics and metabolism of KW-4490, a selective phosphodiesterase 4 inhibitor: Difference in excretion of KW-4490 and acylglucuronide metabolites between rats and cynomolgus monkeys
Xenobiotica·2008· 1 cited
P-glycoprotein Limits the Brain Penetration of Olopatadine Hydrochloride, H1-Receptor Antagonist
Drug Metabolism and Pharmacokinetics·2008· 19 cited
Shortening of the Induction Period of Allergic Asthma in Cynomolgus Monkeys by Ascaris suum and House Dust Mite
Journal of Pharmacological Sciences·2008· 11 citedOpen Access
Inactivation of recombinant human steroid sulfatase by KW-2581
The Journal of Steroid Biochemistry and Molecular Biology·2007· 8 cited
A novel steroidal selective steroid sulfatase inhibitor KW-2581 inhibits sulfated-estrogen dependent growth of breast cancer cells in vitro and in animal models
Breast Cancer Research and Treatment·2007· 31 cited
Evaluation of the Role of the Aquatic Plants in Floating Type Edible Aquatic Plant Purification System
Japanese Journal of Water Treatment Biology·2007· 1 citedOpen Access
Effect of Benidipine on Simvastatin Metabolism in Human Liver Microsomes
Drug Metabolism and Pharmacokinetics·2007· 4 cited
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Frequent Co-authors

Eiichi Fuse(15), Satoshi Kobayashi(14), Yuichi Sugiyama(9), Hiroyuki Kobayashi(9), Noriaki Kurata(7), Hiromi Tanii(6), Edward A. Sausville(5), William D. Figg(5), Donna Headlee(4), Adrian M. Senderowicz(4), Shiro Akinaga(4), Jun Hosogi(4), Rui Ohashi(4), Natsuko Sato(4), Susan G. Arbuck(3), Jiro Kajita(3), K Takai(3), Hiroyuki Ishida(3), Richard A. Messmann(2), Anthony J. Murgo(2)