Dan Rujescu

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

112h-index59.2kcitations911works3.72yr avg
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Research Topics

Genetic Associations and Epidemiology(201), Tryptophan and brain disorders(98), Schizophrenia research and treatment(89), Genetics and Neurodevelopmental Disorders(85), Neurotransmitter Receptor Influence on Behavior(80)

Publications854 total

Effect of polygenic scores on the relationship between psychosis and cognition
Translational Psychiatry·2025Open Access
Exploring penetrance of clinically relevant variants in over 800,000 humans from the Genome Aggregation Database
Nature Communications·2025· 3 citedOpen Access
Polygenic liability to C-reactive protein defines immunometabolic depression phenotypes and influences antidepressant therapeutic outcomes
Genomic psychiatry :·2025· 1 citedOpen Access
Schizophrenia Genetics Modulates Clinical Depressive Features
American Journal of Medical Genetics Part B Neuropsychiatric Genetics·2025Open Access
Genomic analyses reveal new insights into Alzheimer’s disease
2025· 3 cited
Human in vivo assessment of ketamine binding of the serotonin transporter—follow up at a higher dose
Frontiers in Neuroscience·2025Open Access
401. EXPLORING FUNCTIONAL CONNECTIVITY IN ANXIETY: THE ROLE OF THE HIPPOCAMPUS, INSULA, AND AMYGDALA DURING A KETAMINE INFUSION
The International Journal of Neuropsychopharmacology·2025Open Access
Polygenic Hazard Score for Predicting Age-associated Risk of Alzheimer’s Disease in European Populations: Development and Validation
2025· 1 citedOpen Access
Genetic predisposition to unwanted side effects under antidepressants and antipsychotics: a molecular-genetic study of 902 patients over 6 weeks
European Archives of Psychiatry and Clinical Neuroscience·2025Open Access
Machine learning in Alzheimer’s disease genetics
Nature Communications·2025· 5 citedOpen Access
Clinical predictors of treatment resistant depression
European Neuropsychopharmacology·2025· 8 citedOpen Access
Brain glutamate and gamma-aminobutyric acid levels across COVID-19 lockdowns in patients with recurrent major depressive disorder and healthy individuals
Scientific Reports·2025Open Access
Phenotyping extracellular vesicles and their serotonin transporter cargo in major depressive disorder
Journal of Affective Disorders·2025· 3 citedOpen Access
Transferability of European-derived Alzheimer’s disease polygenic risk scores across multiancestry populations
Nature Genetics·2025· 9 citedOpen Access
The impact of depression on functioning: Relation to medication response and other predictors
Psychiatry Research·2025· 1 citedOpen Access
A large-scale multimodal investigation of the interplay between the serotonergic system and emotion processing
Translational Psychiatry·2025Open Access
Predicted plasma proteomics from genetic scores and treatment outcomes in major depression: a meta-analysis
European Neuropsychopharmacology·2025· 2 citedOpen Access
Correction: Mild motor signs and depression: more than just medication side effects?
European Archives of Psychiatry and Clinical Neuroscience·2025Open Access
GWAS meta-analysis of CSF Alzheimer's disease biomarkers 18,948 individuals reveal novel loci and genes regulating lipid metabolism, brain volume and autophagy
2025· 1 citedOpen Access
<i>APOE</i> stratified genome-wide association studies provide novel insights into the genetic etiology of Alzheimers’s disease
2025· 1 citedOpen Access
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Frequent Co-authors

Ina Giegling(26), Srdjan Djurovic(14), Ole A. Andreassen(14), Markus M. Nöthen(13), Hreinn Stefánsson(13), David Collier(12), Marcella Rietschel(11), David St Clair(11), Michael O’Donovan(10), Sven Cichon(10), Engilbert Sigurðsson(10), Pierandrea Muglia(10), Annette M. Hartmann(10), Stacy Steinberg(9), Sarah Tosato(9), Roel A. Ophoff(9), Thomas Werge(9), Michael Gill(8), Hans‐Jürgen Möller(8), Ingrid Melle(8)